Improving prediction for challenging thyroid surgeries

Renovated Prediction Model for Difficult. Transoral and Submental Endoscopic Thyroidectomy

Shanghai 6th People's Hospital · NCT06738888

This study is testing a new way to predict how challenging thyroid surgeries will be by looking at different health factors to help doctors perform the surgery better.

Quick facts

Study typeObservational
Enrollment300 (estimated)
SexAll
SponsorShanghai 6th People's Hospital (other)
Drugs / interventionsradiation
Locations1 site (Shanghai)
Trial IDNCT06738888 on ClinicalTrials.gov

What this trial studies

This study aims to renovate and validate a prediction model for difficult transoral and submental endoscopic thyroidectomy based on various clinical factors. The researchers will assess indicators such as male sex, age, BMI, neck length, and specific thyroid diseases to enhance surgical outcomes. By integrating innovative measurements like neck circumference and distances related to neck extension, the study seeks to improve the training and execution of this surgical approach. The ultimate goal is to promote the transoral and submental endoscopic technique for thyroid surgeries.

Who should consider this trial

Good fit: Ideal candidates include individuals diagnosed with differentiated thyroid cancer or benign thyroid nodules that meet specific size criteria.

Not a fit: Patients with prior neck surgeries, significant neck restrictions, or evidence of extrathyroidal invasion may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical outcomes and reduced complications for patients undergoing thyroid surgery.

How similar studies have performed: While previous studies have proposed prediction models for thyroid surgeries, this approach integrates novel measurements and is aimed at validating those models in a prospective manner.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Clinical diagnosis of differentiated thyroid cancer with a maximum diameter not exceeding 4 cm
* Clinical diagnosis of benign thyroid nodule with a maximum diameter not exceeding 6 cm
* Absence of suspicious lateral lymph nodes or distant metastases

Exclusion Criteria:

* Participants with fusion or fixation of lymph nodes in the neck
* Participants with history of neck surgery or radiation
* Participants with vocal fold fixation by preoperative fibrolaryngoscope
* Participants with preoperative examination suggestive of extrathyroidal invasion
* Participants with a significantly restricted neck and/or jaw

Where this trial is running

Shanghai

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Thyroid Cancer, Thyroid Diseases, Thyroid Nodule, Endoscopic thyroidectomy, Transoral and submental approach, Prediction model

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.