Improving pain relief after knee replacement surgery with additional nerve blocks
Evaluation of the Analgesic Benefit of Adding the Blocks of the Intermediate and Medial Femoral Cutaneous Nerves in Addition to the Femoral Triangle Block for Postoperative Analgesia After a Knee Replacement Surgery: A Randomized Controlled Clinical Trial
This study is testing if adding extra nerve blocks to the usual pain relief method after knee replacement surgery can help patients feel less pain and recover faster.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 122 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre hospitalier de l'Université de Montréal (CHUM) Academic / other |
| Locations | 1 site (Montreal, Quebec) |
| Trial ID | NCT06038851 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of adding intermediate and medial femoral cutaneous nerve blocks to the standard femoral triangle block for postoperative pain management in patients undergoing total knee replacement surgery. The aim is to enhance analgesia and facilitate early mobilization, which is crucial for recovery. By utilizing a multimodal approach to pain relief, the study seeks to determine if this combined nerve block technique can provide better outcomes compared to traditional methods. The research will involve a randomized controlled design to assess the analgesic benefits in the target population.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and over who are scheduled for primary total knee arthroplasty and classified as ASA 1 to 3.
Not a fit: Patients who may not benefit include those with chronic pain requiring high doses of opioids, contraindications to nerve blocks, or those unable to communicate effectively with the healthcare team.
Why it matters
Potential benefit: If successful, this approach could significantly improve pain management and recovery times for patients after knee replacement surgery.
How similar studies have performed: While some preliminary studies have explored similar nerve block techniques, this specific approach has not been extensively tested in a randomized controlled setting.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years and over, requiring a primary total knee arthroplasty * 'American Society of Anesthesiologists' classification 1 to 3 Exclusion Criteria: * Refusal or unable to consent * Contraindications to a peripheral nerve block; * Inability to communicate with the healthcare team or the research team; * Inability to understand follow-up instructions or questionnaires; * Chronic pain requiring the intake of the equivalent of more than 60 mg of morphine daily; * Pregnancy; * Patients weighing less than 50 kg (to limit the risk of intoxication with local anesthetics).
Where this trial is running
Montreal, Quebec
- Centre Hospitalier de l'Université de Montréal (CHUM) — Montreal, Quebec, Canada (Recruiting)
Study contacts
- Principal investigator: Maxim Roy, MD, FRCPC — Centre hospitalier de l'Université de Montréal (CHUM)
- Study coordinator: Maxim Roy, MD, FRCPC
- Email: maxim.roy20@gmail.com
- Phone: 514-890-8000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.