Improving pain management after prostate surgery
Optimizing Pain Control in Transurethral Resection of the Prostate
This study is testing a new way to manage pain after prostate surgery that uses different pain relief methods instead of just opioids to see if it can help patients feel better while reducing opioid use.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | Male |
| Sponsor | Benaroya Research Institute Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Seattle, Washington) |
| Trial ID | NCT04102566 on ClinicalTrials.gov |
What this trial studies
This study aims to develop a multi-modal protocol for pain management following transurethral resection of the prostate (TURP) that reduces reliance on opioids. Patients will be randomized to receive either the standard care, which primarily uses opioids, or the new multi-modal approach that combines different analgesic agents, including ibuprofen, along with education on pain control. The goal is to achieve effective pain relief while minimizing opioid use, thereby addressing concerns related to the opioid epidemic. The findings could lead to new guidelines for pain management in TURP and potentially other urologic procedures.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who are scheduled for TURP and proficient in English.
Not a fit: Patients who have recently filled an opioid prescription or have contraindications to the medications used in the study may not benefit.
Why it matters
Potential benefit: If successful, this approach could provide effective pain relief for patients while significantly reducing opioid consumption.
How similar studies have performed: Other studies have shown promise in using multi-modal pain management strategies, suggesting this approach could be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Are identified as candidates for TURP * Are 18 years of age or greater * Are proficient in English Exclusion Criteria: * Have filled an opioid prescription in the last 2 months * Have an allergy to a medication included in the protocol * Have a history of pelvic radiation * Have renal failure (Serum Cr \> 2.0 mg/dl), peptic ulcer disease, history of gastric bypass, cirrhosis, or other contraindication precluding use of NSAID's * Have liver failure, hepatitis, or alcohol abuse which precludes use of acetaminophen
Where this trial is running
Seattle, Washington
- Virginia Mason Medical Center — Seattle, Washington, United States (Recruiting)
Study contacts
- Study coordinator: Ryan Donahue, MD
- Email: ryan.donahue@vmmc.org
- Phone: 2062236600
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.