Improving pain management after prostate surgery
Official title: Optimizing Pain Control in Transurethral Resection of the Prostate
Run by Benaroya Research Institute · NCT04102566 · Data updated 2026-11-12
This study is testing a new way to manage pain after prostate surgery that uses different pain relief methods instead of just opioids to see if it can help patients feel better while reducing opioid use.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years and up |
| Sex | Men only |
| Enrollment | 50 (estimated) |
| Sponsor | Benaroya Research Institute Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Seattle, Washington) |
| Status | Recruiting |
| Started | December 8, 2017 |
| Main results expected | October 1, 2019 |
| Study ends | December 1, 2019 |
| Registry record updated | September 27, 2019 |
| Trial ID | NCT04102566 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older who are scheduled for TURP and proficient in English.
✕Probably not a fit
Patients who have recently filled an opioid prescription or have contraindications to the medications used in the study may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to develop a multi-modal protocol for pain management following transurethral resection of the prostate (TURP) that reduces reliance on opioids. Patients will be randomized to receive either the standard care, which primarily uses opioids, or the new multi-modal approach that combines different analgesic agents, including ibuprofen, along with education on pain control. The goal is to achieve effective pain relief while minimizing opioid use, thereby addressing concerns related to the opioid epidemic. The findings could lead to new guidelines for pain management in TURP and potentially other urologic procedures.
Why it matters
Potential benefit: If successful, this approach could provide effective pain relief for patients while significantly reducing opioid consumption.
How similar studies have gone: Other studies have shown promise in using multi-modal pain management strategies, suggesting this approach could be effective.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Are identified as candidates for TURP * Are 18 years of age or greater * Are proficient in English Exclusion Criteria: * Have filled an opioid prescription in the last 2 months * Have an allergy to a medication included in the protocol * Have a history of pelvic radiation * Have renal failure (Serum Cr \> 2.0 mg/dl), peptic ulcer disease, history of gastric bypass, cirrhosis, or other contraindication precluding use of NSAID's * Have liver failure, hepatitis, or alcohol abuse which precludes use of acetaminophen
Where it's running
-
Virginia Mason Medical Center
Seattle, Washington, United States Recruiting
Study contacts
- Study coordinator: Ryan Donahue, MD
- Email: ryan.donahue@vmmc.org
- Phone: 2062236600
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Thulio versus Holmium lasers for removing enlarged prostate tissue
This trial will test whether the new pulsed Thulio (thulium) laser works as well as the standard holmium laser for men with enlarged prostates and urinary symptoms.
-
Comparing two treatments for urinary retention in men with BPH
This study is testing whether a new procedure called prostatic urethral lift works better than the traditional surgery for helping men with urinary retention caused by an enlarged prostate.
-
Noninvasive ultrasound assessment of bladder function
This study is testing a new ultrasound method to see if it can help identify bladder problems in men with benign prostatic hyperplasia (BPH) and guide their treatment.
-
Using loop diuretics to improve same-day discharge after prostate surgery
This study is testing if giving a diuretic during prostate surgery can help men go home the same day by improving their recovery and reducing complications.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.