Using loop diuretics to improve same-day discharge after prostate surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the impact of intra-operative administration of furosemide on same-day discharge rates following Holmium Laser Enucleation of the Prostate (HoLEP) for benign prostatic hypertrophy (BPH). Patients will be randomly assigned to receive either 20mg of IV furosemide or a control treatment during the procedure. The study aims to determine if the use of furosemide significantly affects post-operative urinary output and reduces complications such as hematuria, thereby facilitating same-day discharge. The trial is conducted at Northwestern University and involves male patients aged 18 to 89 undergoing HoLEP.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Males 18 -89 undergoing HoLEP
* Willing to sign the Informed Consent Form
* Able to read, understand, and complete patient questionnaires.

Exclusion Criteria:

* Allergy or hypersensitivity to furosemide or other loop diuretic
* Anuric patients or patients with liver failure
* Patients having a concurrent ureteroscopy +/- laser lithotripsy, percutaneous nephrolithotomy, or non-urologic surgery at the time of their HoLEP
* Anticipated need for perineal urethrostomy at the time of HoLEP
* Patient not undergoing catheter removal and voiding trial at Northwestern Memorial Hospital

Where it's running

• Northwestern University
  Chicago, Illinois, United States Recruiting

Study contacts

• Principal investigator: Amy E Krambeck, MD — Northwestern Medicine
• Study coordinator: Nicholas S Dean, MD
• Email: nicholas.dean@northwestern.edu
• Phone: 7806906285

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.