Comparing two treatments for urinary retention in men with BPH

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study is a prospective, randomized controlled trial that compares the effectiveness of prostatic urethral lift (PUL) versus transurethral resection of prostate (TURP) in male patients suffering from benign prostate hyperplasia (BPH) with urinary retention. The primary goal is to evaluate the rates of catheter-free recovery between the two procedures. Secondary objectives include assessing complication rates, cost-effectiveness, patient satisfaction, symptom scores, quality of life, and urodynamic parameters. Eligible participants will undergo a series of assessments before being randomized to one of the two treatment groups, with follow-up evaluations scheduled over five years.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Male patients
* age \>40 years old
* urinary retention who failed trial without catheter

Exclusion Criteria:

* Inability to provide consent OR no guardians or relatives to help provide consent on patient's behalf
* Active urinary tract infection
* Previous surgical treatment for benign prostatic hyperplasia (i.e., TURP, prostatic urethral lift, etc.)
* Bladder stones
* Urethral strictures or bladder neck contractures
* Prostate size \>100mL
* Solely obstructing median lobe
* Urinary retention not due to obstruction (i.e., Bladder outflow obstruction index \<20 on urodynamic studies)
* Poor detrusor contractility (maximum detrusor pressure \<20cmH2O during voiding phase)
* Anticoagulant or antiplatelet agents that cannot be stopped

Where it's running

• Queen Mary Hospital
  Hong Kong, China Recruiting

Study contacts

• Principal investigator: Brian SH Ho, MBBS — Queen Mary Hospital, Hong Kong
• Study coordinator: Brian SH Ho, MBBS
• Email: hobrian@hku.hk
• Phone: (852)2255-3023

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.