Improving oral and systemic health in people with prediabetes using personalized hygiene advice

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to enhance oral and systemic health in individuals with prediabetes by providing personalized oral hygiene advice through either dental professionals or artificial intelligence (AI). It recognizes the link between gum disease and prediabetes, where controlling gum inflammation can improve blood glucose levels. Participants will receive tailored guidance on maintaining oral hygiene, which is crucial for managing their condition. The study will compare the effectiveness of AI-generated advice versus traditional advice from dental professionals.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* \- Subjects who are \>18 years of age and able to give informed consent.
* \- Subjects who are mentally and cognitively healthy.
* \- Subjects who have at least 6 anterior maxillary or mandibular natural teeth including incisors and canine.
* \- Subjects who are with prediabetic state with impaired HbA1c 5.7% to 6.4%, impaired fasting plasma glucose level 5.6mmol/L to 6.9 mmol/L and/or impaired plasma glucose level after 2h OGTT 7.8 mmol/L to 11.0 mmol/L.
* \- Subjects who can speak, read, or understand Cantonese to complete the satisfaction questionnaire.
* \- Subjects who can practice oral hygiene procedure (regular tooth brushing and interdental cleansing/flossing/brushing) daily on their own independently.

Exclusion Criteria:

* \- Subjects who have less than 6 anterior maxillary or mandibular natural teeth with or without dental prostheses in those area.
* \- Subjects who are with a current diagnosis or clinical history of T2DM.
* \- Subjects who have mental illness, or similar problems that unable to complete the satisfaction questionnaire.
* \- Subjects who cannot perform oral hygiene procedure (regular tooth brushing and interdental cleansing/flossing/brushing) by any condition of oral cavity such as tumor or maxillomandibular fixation.

Where it's running

• Prince Philip Dental Hospital
  Hong Kong, Sai Ying Pun, Hong Kong Recruiting

Study contacts

• Principal investigator: Walter Y.H. Lam, Prof. — The University of Hong Kong
• Study coordinator: Walter Y.H. Lam, Prof.
• Email: retlaw@hku.hk
• Phone: (852) 28590306

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.