Improving nutrition for patients undergoing joint replacement surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the impact of nutritional interventions on patients with malnutrition who are scheduled for total joint arthroplasty. It aims to assess how oral nutritional supplementation can affect hematological markers and overall outcomes in these patients. By screening for malnutrition and providing targeted nutritional support, the study seeks to optimize pre-operative care and improve recovery after surgery. This is a novel approach, as no previous randomized control study has focused on this aspect in total joint arthroplasty patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patient are current candidates for elective primary total hip and total knee arthroplasty
2. Patients ≥55 years of age but ≤ 95
3. Patients who meet at least one of the following three laboratory criteria for malnutrition:

TSerum Albumin: ≤3.5 mg/dl Pre-Albumin: \<15 mg/dl Transferrin: \<200 mg/dl

Exclusion Criteria:

1. Previous history of septic arthritis
2. Allergy to oral supplementation
3. Inability to consume oral supplementation
4. Protein malabsorption syndromes
5. Eating disorders
6. End stage renal and hepatic disease
7. Revision surgery, non-elective surgery, hemiarthroplasty, and unicompartmental knee arthroplasty

Where it's running

• NYU Langone Health
  New York, New York, United States Recruiting
• Rothman Orthopedic Institute
  Philadelphia, Pennsylvania, United States Recruiting

Study contacts

• Principal investigator: Ran Schwarzkopf — NYU Langone
• Study coordinator: Daniel Waren
• Email: Daniel.waren@nyulangone.org
• Phone: 212-598-6245

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.