Weight-bearing dangling exercises vs VMOb NMES for knee osteoarthritis
Official title: Effectiveness of Weighted Dangling Exercises Versus Vastus Medialis Oblique Muscle Neuromuscular Stimulation in Patients With Knee Osteoarthritis
Run by University of Lahore · NCT07701174 · Data updated 2026-11-12
This study tests whether weighted dangling exercises or VMOb muscle NMES help people with knee osteoarthritis.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years to 60 Years |
| Sex | All |
| Enrollment | 48 (estimated) |
| Sponsor | University of Lahore Academic / other |
| Locations | 1 site (Lahore, Punjab Province) |
| Status | Recruiting |
| Started | May 25, 2026 |
| Main results expected | August 25, 2026 |
| Study ends | September 10, 2026 |
| Registry record updated | July 14, 2026 |
| Trial ID | NCT07701174 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 40–60 with clinically and radiographically confirmed knee osteoarthritis (Kellgren-Lawrence grade 2 or higher) experiencing at least 6 months of unilateral knee pain and crepitus.
✕Probably not a fit
Individuals with recent knee surgery, knee joint replacement history, certain neuromuscular or systemic disorders, or recent corticosteroid injections may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized controlled trial will compare weighted dangling exercises to a combination of vastus medialis oblique strengthening and neuromuscular electrical stimulation in adults with knee osteoarthritis. Forty-eight participants aged 40–60 years will be recruited and randomized to one of two 8-week, thrice-weekly supervised interventions. Outcomes include pain on the numeric rating scale, functional disability scores, and muscle strength, assessed at baseline, 4 weeks, and 8 weeks, with data analyzed using appropriate statistical tests. The study aims to determine which approach offers greater symptom relief and functional improvement.
Why it matters
Potential benefit: If successful, the more effective intervention could provide better pain relief and improved knee function for people with knee OA.
How similar studies have gone: Previous work in similar non-pharmacologic strategies for knee OA has shown potential benefits, but direct head-to-head comparisons of these two approaches are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Both genders and aged between 40 and 60 years. Symptoms of unilateral knee pain and crepitus persist for at least 6 months during ascending and descending motion. Radiographic KOA; grade 2 or more according to Kellgren and Lawrence scale. Patient referred by an orthopedic physician Those who have taken oral corticosteroids within the last month or who received intra-articular corticosteroid injection or analgesic injection intervention for hip or knee pain within the last 3 month Exclusion Criteria: * Recent surgery (within three months) history of hip or knee joint replacement, tibial osteotomy, orthoses with systemic arthritis, history of trauma such as knee fracture and other with muscular disease of neurological disorders that would affect lower extremity function is excluded.
Where it's running
-
University of Lahore Teaching Hospital, Lahore, Pakistan
Lahore, Punjab Province, Pakistan Recruiting
Study contacts
- Principal investigator: Mahnoor Fatima, MS MSK* — University Institute of Physical Therapy, University of Lahore
- Study coordinator: Ishaq Ahmed, PhD PT
- Email: ishaq.ahmed@uipt.uol.edu.pk
- Phone: 03344066463
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Autologous adipose-derived stem cell injections for knee osteoarthritis
We’re testing whether injecting a patient’s own fat-derived stem cells into the knee can help people with knee OA feel less pain and move better, compared with a standard hyaluronic acid treatment.
-
Early wear of a Vitamin E-infused liner in a dual-mobility hip replacement
This study tests whether a Vitamin E-infused liner in a dual-mobility hip implant wears as little as a conventional liner over two years in adults needing hip replacement.
-
Preoperative Music to Ease Anxiety Before Hip or Knee Replacement
Patients awaiting hip or knee replacement listen to their own music through noise‑canceling headphones to see if it lowers preoperative anxiety.
-
Post-op prednisone vs standard steroid regimen after knee or hip replacement
This study tests a 5-day oral prednisone course after knee or hip replacement to see if pain, swelling, and glucose control are better or different than the usual intraoperative steroid approach.
-
AI-based prediction of five major diseases using integrated health data
Researchers are testing an AI model to see if they can predict the onset of five major diseases in adults 30–65 by combining medical records with biospecimens and lifestyle data.
-
Personalized total knee replacement: computer navigation versus robotic-arm assistance
We test whether robotic-arm assistance or computer navigation during personalized total knee replacement gives adults with knee osteoarthritis a more natural-feeling knee and better function.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.