Clinical trial Recruiting at 1 site Interventional Ages 40 to 60

Weight-bearing dangling exercises vs VMOb NMES for knee osteoarthritis

Official title: Effectiveness of Weighted Dangling Exercises Versus Vastus Medialis Oblique Muscle Neuromuscular Stimulation in Patients With Knee Osteoarthritis

Run by University of Lahore · NCT07701174 · Data updated 2026-11-12

This study tests whether weighted dangling exercises or VMOb muscle NMES help people with knee osteoarthritis.

Quick facts

Study typeInterventional
Ages40 Years to 60 Years
SexAll
Enrollment48 (estimated)
SponsorUniversity of Lahore
Academic / other
Locations1 site (Lahore, Punjab Province)
StatusRecruiting
StartedMay 25, 2026
Main results expectedAugust 25, 2026
Study endsSeptember 10, 2026
Registry record updatedJuly 14, 2026
Trial IDNCT07701174 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 40–60 with clinically and radiographically confirmed knee osteoarthritis (Kellgren-Lawrence grade 2 or higher) experiencing at least 6 months of unilateral knee pain and crepitus.

Probably not a fit

Individuals with recent knee surgery, knee joint replacement history, certain neuromuscular or systemic disorders, or recent corticosteroid injections may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial will compare weighted dangling exercises to a combination of vastus medialis oblique strengthening and neuromuscular electrical stimulation in adults with knee osteoarthritis. Forty-eight participants aged 40–60 years will be recruited and randomized to one of two 8-week, thrice-weekly supervised interventions. Outcomes include pain on the numeric rating scale, functional disability scores, and muscle strength, assessed at baseline, 4 weeks, and 8 weeks, with data analyzed using appropriate statistical tests. The study aims to determine which approach offers greater symptom relief and functional improvement.

Why it matters

Potential benefit: If successful, the more effective intervention could provide better pain relief and improved knee function for people with knee OA.

How similar studies have gone: Previous work in similar non-pharmacologic strategies for knee OA has shown potential benefits, but direct head-to-head comparisons of these two approaches are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Both genders and aged between 40 and 60 years. Symptoms of unilateral knee pain and crepitus persist for at least 6 months during ascending and descending motion. Radiographic KOA; grade 2 or more according to Kellgren and Lawrence scale. Patient referred by an orthopedic physician Those who have taken oral corticosteroids within the last month or who received intra-articular corticosteroid injection or analgesic injection intervention for hip or knee pain within the last 3 month

Exclusion Criteria:

* Recent surgery (within three months) history of hip or knee joint replacement, tibial osteotomy, orthoses with systemic arthritis, history of trauma such as knee fracture and other with muscular disease of neurological disorders that would affect lower extremity function is excluded.

Where it's running

  • University of Lahore Teaching Hospital, Lahore, Pakistan
    Lahore, Punjab Province, Pakistan
    Recruiting

Study contacts

  • Principal investigator: Mahnoor Fatima, MS MSK* — University Institute of Physical Therapy, University of Lahore
  • Study coordinator: Ishaq Ahmed, PhD PT
  • Email: ishaq.ahmed@uipt.uol.edu.pk
  • Phone: 03344066463

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.