Improving maternal-fetal health through innovative ultrasound and community support

Community-based Fetal Ultrasound and Care Navigation: An Approach to Engaging Pregnant Women With Substance Use Disorder in Prenatal Care and Substance Use Treatment

Not applicable Interventional Virginia Commonwealth University · NCT05814575

This study is testing a new approach that combines special ultrasound techniques and community support to help pregnant people with substance use disorders get better care for themselves and their babies.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 45 Years
SexAll
SponsorVirginia Commonwealth University Academic / other
Locations1 site (Richmond, Virginia)
Trial IDNCT05814575 on ClinicalTrials.gov

What this trial studies

This exploratory study aims to enhance health equity for mother-infant pairs affected by substance use disorders by implementing a community-informed intervention. It utilizes a novel fetal ultrasound protocol alongside motivational interviewing and care coordination strategies to engage pregnant individuals in early and consistent prenatal care. The intervention focuses on fostering a connection between the mother and fetus, which is expected to motivate healthier behaviors and improve health outcomes. By addressing the unique challenges faced by this population, the study seeks to reduce health disparities and promote better maternal and infant health.

Who should consider this trial

Good fit: Ideal candidates for this study are pregnant individuals aged 18 to 45, between 22-32 weeks gestation, who have a history of substance use disorder or are currently in treatment.

Not a fit: Patients with cognitive impairments, psychiatric instability, or known fetal anomalies may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved prenatal care and health outcomes for mothers and their infants affected by substance use disorders.

How similar studies have performed: While this approach is innovative, similar community-based interventions have shown promise in improving health outcomes, suggesting potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Pregnant persons, Aged 18 through 45, between 22-32 weeks gestation at study entry
* Provision of signed and dated informed consent form
* Not incarcerated
* Able to read and understand English
* For infants after delivery, parental informed consent to participate in the study
* Stated willingness to comply with all study procedures
* Meets Diagnostic and Statistical Manual 5 criteria for Substance Abuse or substance use disorder in the last 12 months or is in active treatment for substance use disorder (including Nicotine/Tobacco, alcohol, marijuana, illicit and licit substances, and opioids) or actively using substances during pregnancy.
* Willingness to participate in the NEXUS regimen

Exclusion Criteria:

* Presenting with cognitive impairment
* psychiatric instability (active psychosis or acute mania)
* language or legal barriers that would limit the patient's ability to provide informed consent and complete research assessments.
* Known fetal anomalies
* Medical conditions requiring frequent ultrasound monitoring outside the study (e.g.

Gestational Diabetes)

Where this trial is running

Richmond, Virginia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Pregnancy RelatedSubstance UseMental Health Issue
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.