Improving lung cancer risk prediction for never-smokers in Taiwan

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to enhance the accuracy of lung cancer risk prediction models specifically for never-smokers in Taiwan. It involves validating existing models by integrating environmental and occupational factors, as well as assessing autoantibodies and genetic markers associated with lung cancer. The study will utilize machine learning algorithms to optimize these models and collect urine samples for further analysis. By focusing on the unique demographic of never-smokers, the research seeks to address the rising incidence of lung cancer in this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age 50-80 years old
2. First-degree relatives of lung cancer patients

   * aged more than 50 - 80 years old
   * or older than the age at diagnosis of the youngest lung cancer the proband in the family if they are less than 50 years old

Exclusion Criteria:

1. Previous history of lung cancer
2. Another malignancy except for cervical carcinoma in situ or non-melanomatous carcinoma of the skin within 5 years
3. An inability to tolerate transthoracic procedures or thoracotomy
4. Chest CT examination was performed within 18 months
5. Hemoptysis of unknown etiology within one month
6. Body weight loss of more than 6 kg within one year without an evident cause
7. A known pregnancy

Where it's running

• Chung Shan Medical University Hospital
  Taichung, Taiwan, Taiwan Recruiting
• National Taiwan University Hospital Hsin-Chu Branch
  Hsinchu, Taiwan Recruiting
• Hualien Tzu Chi Hospital
  Hualien City, Taiwan Recruiting
• Kaohsiung Medical University Chung-Ho Memorial Hospital
  Kaohsiung City, Taiwan Recruiting
• National Taiwan University Hospital
  Taipei, Taiwan Recruiting
• E-Da Hospital
  Kaohsiung City, Taiwan Not yet recruiting

Study contacts

• Study coordinator: GEECHEN CHANG, MD. PhD
• Email: geechen@gmail.com
• Phone: +886-4-24739595

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.