Improving knee replacement outcomes using a pressure sensor for alignment
Official title: Balancing Kinematically Aligned Total Knee Replacements During Total Primary Knee Arthroplasty Using Verasense
Run by Nova Scotia Health Authority · NCT03286868 · Data updated 2026-11-12
This study tests if using a special pressure sensor during knee replacement surgery can help people with osteoarthritis walk better and feel more satisfied with their results compared to standard surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 21 Years to 80 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Nova Scotia Health Authority Academic / other |
| Locations | 1 site (Halifax, Nova Scotia) |
| Status | Recruiting |
| Started | July 23, 2018 |
| Main results expected | September 2026 |
| Study ends | September 2026 |
| Registry record updated | February 17, 2025 |
| Trial ID | NCT03286868 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 21 to 80 with symptomatic knee arthritis requiring total knee arthroplasty and who have varus alignment.
✕Probably not a fit
Patients with inflammatory arthritis, severe obesity, or those unable to provide consent may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial evaluates the effectiveness of using the Verasense pressure sensor to optimize the alignment of total knee replacements (TKR) during surgery for patients with osteoarthritis. It involves a randomized controlled design where participants will either receive a kinematically aligned TKR with the guidance of the Verasense sensor or a standard TKR without sensor data. The primary focus is on assessing postoperative gait and patient satisfaction, while secondary outcomes include the number of soft tissue releases during surgery. The goal is to determine if sensor-guided alignment leads to better functional outcomes compared to traditional methods.
Why it matters
Potential benefit: If successful, this approach could lead to higher patient satisfaction and improved mobility after knee replacement surgery.
How similar studies have gone: Previous studies have shown promise in using sensor technology for surgical alignment, suggesting potential for success in this novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Symptomatic arthritis of the knee indicating primary total knee arthroplasty * Between the ages of 21 and 80 inclusive * Patients willing and able to comply with follow-up requirements and self-evaluations * Ability to give informed consent * Varus alignment Exclusion Criteria: * Patients less than 21 years of age, or 81 years of age and older * Unable to provide consent * BMI \>45 * Pregnancy * Patients with inflammatory arthritis, posttraumatic osteoarthritis, post high tibial osteotomy, or arthritis due to sepsis will be excluded. * Active or prior infection * Medical condition precluding major surgery * Severe osteoporosis or osteopenia * Neuromuscular impairment * Significant co-morbidity affecting ability to ambulate * Valgus alignment
Where it's running
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Nova Scotia Health Authority
Halifax, Nova Scotia, Canada Recruiting
Study contacts
- Study coordinator: Research Manager
- Email: elise.laende@nshealth.ca
- Phone: 902-473-3883
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.