Improving imaging techniques for Moyamoya Disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to enhance patient care for individuals with Moyamoya Disease by investigating various imaging technologies to better understand cerebral hemodynamics and disease progression. It involves analyzing CO2-triggered BOLD fMRI in comparison to H2 15O PET/CT, as well as examining longitudinal changes in vessel-wall imaging and correlating these with biosampling. The goal is to establish standardized imaging recommendations for pre- and postoperative assessments in Moyamoya patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with suspicion of Moyamoya Disease
* Patients able to understand the study and to give their informed consent

Exclusion Criteria:

* Cerebral vascular disease caused by atherosclerosis
* Vasculitis
* Contraindications to MRI
* Contraindications to PET/CT
* Pregnancy
* Inability to give informed consent
* Renal insufficiency

Where it's running

• University of Tuebingen, Neurosurgery
  Tübingen, Baden-Wurttemberg, Germany Recruiting

Study contacts

• Study coordinator: Constantin Roder, Prof. Dr., MD
• Email: constantin.roder@med.uni-tuebingen.de
• Phone: 0049-7071290

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Risk prediction for stroke and cognitive decline in Moyamoya disease and Moyamoya syndrome

  A large multicenter study tests whether combining clinical data, imaging, lab and genetic information can predict who will have stroke or cognitive decline among people with Moyamoya.

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality and 12 other locations · NCT07894107

• 5T MRI and Metabolomics to Predict Hemorrhage Risk in Moyamoya Disease

  This study tests whether advanced 5T MRI imaging and metabolomics can help predict which moyamoya patients are at higher risk of intracranial hemorrhage.

  Recruiting Beijing Hospital · Beijing, Beijing Municipality · NCT07781579

• XR-assisted CT-guided localization for EC-IC bypass in Moyamoya and chronic cerebral ischemia

  The study tests whether a metaverse-based surgical simulation with extended reality helps localize vessels during EC-IC bypass for moyamoya disease or chronic cerebral ischemia.

  Recruiting National Taiwan University Hospital · Taipei · NCT07711457

• Family screening and early detection for moyamoya disease

  This project will try to find biological signs and 5T high-resolution MRI features that could detect moyamoya earlier in people with the disease, their first-degree relatives, and people without a family history.

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality · NCT07517354

• Remimazolam: target-controlled infusion versus manual infusion during cerebrovascular bypass

  This trial will test whether target-controlled infusion uses less remimazolam than manual infusion in adults undergoing cerebrovascular bypass surgery for moyamoya disease.

  Recruiting Seoul National University Hospital · Seongnam-si, Gyeonggi-do · NCT07377695

• Cardiac index–guided blood flow management during pediatric Moyamoya EDAS surgery

  This study will test whether using each child's cardiac index to guide fluids and hemodynamic care during EDAS lowers postoperative transient ischemic episodes in children with Moyamoya disease.

  Recruiting Seoul National University Hospital · Seoul · NCT07304947

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.