Cardiac index–guided blood flow management during pediatric Moyamoya EDAS surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, randomized 1:1 trial comparing goal-directed intraoperative hemodynamic management guided by baseline cardiac index versus standard blood pressure–based management in children undergoing encephaloduroarteriosynangiosis (EDAS). Children under 18 with Moyamoya disease scheduled for EDAS under general anesthesia are randomized to one of the two management strategies. The intervention arm uses individualized cardiac index targets to direct fluids and vasoactive drugs, while the control arm follows standard arterial pressure targets. The primary outcome is the incidence of transient ischemic episodes during the hospitalization after surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Pediatric patients \<18 years undergoing EDAS for Moyamoya disease under general anesthesia

Exclusion Criteria:

* ASA physical status 4-5
* Emergency surgery
* Known cardiovascular disease
* Any condition judged inappropriate by investigators

Where it's running

• Seoul National University Children's Hospital
  Seoul, South Korea Recruiting

Study contacts

• Study coordinator: Jung-Bin Park
• Email: jb4001@snu.ac.kr
• Phone: 820220723664

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.