Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Improving heart failure treatment through electronic alerts to doctors

Official title: PRagmatic Trial Of Messaging to Providers About Treatment of Heart Failure (PROMPT-HF) at Inova

Run by Inova Health Care Services · NCT05433220 · Data updated 2026-11-12

This study tests if sending alerts to doctors about heart failure medications can help patients get the right treatment and feel better.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment5000 (estimated)
SponsorInova Health Care Services
Academic / other
Locations1 site (Falls Church, Virginia)
StatusRecruiting
StartedAugust 25, 2022
Main results expectedJune 2027
Study endsAugust 25, 2027
Registry record updatedJuly 13, 2026
Trial IDNCT05433220 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults over 18 years old with heart failure and a left ventricular ejection fraction of 40% or less who are seen by a cardiologist at Inova.

Probably not a fit

Patients receiving hospice care, those who have opted out of EHR-based research, or those already on maximally titrated doses of heart failure medications may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial evaluates the effectiveness of an electronic health record best practice advisory system designed to alert clinicians about guideline-recommended heart failure medications that are not currently prescribed to their patients. It compares this intervention to usual care practices in outpatient clinics and hospitals within the Inova Health System. The goal is to enhance medication prescription for patients with heart failure and reduced ejection fraction, thereby improving patient outcomes.

Why it matters

Potential benefit: If successful, this approach could lead to better management of heart failure and improved patient health outcomes.

How similar studies have gone: Previous studies have shown that electronic health record interventions can improve adherence to treatment guidelines, suggesting potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age\>18 Years
* Seen by a Cardiologist in an Inova clinic or Inova hospital setting
* Left Ventricular Ejection Fraction ≤40%

Exclusion Criteria:

* Opted out of EHR-based research
* Hospice care
* Already receiving maximally titrated doses of each of the four classes of evidence- based HFrEF medical therapy
* Prior heart transplant

Where it's running

  • Inova Health System
    Falls Church, Virginia, United States
    Recruiting

Study contacts

  • Principal investigator: Mitchell Psotka, MD, PhD — Inova Health Care Services
  • Study coordinator: Matthew G Dimond, BS
  • Email: matthew.dimond@inova.org
  • Phone: 7037762828

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.