Improving heart failure treatment through electronic alerts to doctors

PRagmatic Trial Of Messaging to Providers About Treatment of Heart Failure (PROMPT-HF) at Inova

Not applicable Interventional Inova Health Care Services · NCT05433220

This study tests if sending alerts to doctors about heart failure medications can help patients get the right treatment and feel better.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment5000 (estimated)
Ages18 Years and up
SexAll
SponsorInova Health Care Services Academic / other
Locations1 site (Falls Church, Virginia)
Trial IDNCT05433220 on ClinicalTrials.gov

What this trial studies

This trial evaluates the effectiveness of an electronic health record best practice advisory system designed to alert clinicians about guideline-recommended heart failure medications that are not currently prescribed to their patients. It compares this intervention to usual care practices in outpatient clinics and hospitals within the Inova Health System. The goal is to enhance medication prescription for patients with heart failure and reduced ejection fraction, thereby improving patient outcomes.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old with heart failure and a left ventricular ejection fraction of 40% or less who are seen by a cardiologist at Inova.

Not a fit: Patients receiving hospice care, those who have opted out of EHR-based research, or those already on maximally titrated doses of heart failure medications may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to better management of heart failure and improved patient health outcomes.

How similar studies have performed: Previous studies have shown that electronic health record interventions can improve adherence to treatment guidelines, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age\>18 Years
* Seen by a Cardiologist in an Inova clinic or Inova hospital setting
* Left Ventricular Ejection Fraction ≤40%

Exclusion Criteria:

* Opted out of EHR-based research
* Hospice care
* Already receiving maximally titrated doses of each of the four classes of evidence- based HFrEF medical therapy
* Prior heart transplant

Where this trial is running

Falls Church, Virginia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Heart FailureGDMTNYHAHFrEFImplementation
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.