Improving healthcare conversations for patients with memory issues and their caregivers

Hybrid Efficacy-effectiveness Trial to Promote Goals-of-care Discussions for Patients With Alzheimer's Disease and Related Dementias and Their Family Caregivers

Not applicable Interventional University of Washington · NCT05596760

This study is testing a new tool called the 'Jumpstart Guide' to see if it helps older patients with memory issues and their caregivers have better conversations about healthcare goals during doctor visits.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment1800 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Washington Academic / other
Locations3 sites (Seattle, Washington and 2 other locations)
Trial IDNCT05596760 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to enhance communication between clinicians, patients with memory problems, and their family members by implementing a tool called the 'Jumpstart Guide.' This guide is designed to facilitate discussions about patients' healthcare goals during outpatient visits. Patients aged 55 and older with documented memory issues will be randomly assigned to either receive the Jumpstart Guide or standard care. The effectiveness of the intervention will be assessed by comparing the documentation of goals-of-care discussions in electronic health records between the two groups.

Who should consider this trial

Good fit: Ideal candidates for this study are outpatient individuals aged 55 and older with a diagnosis of Alzheimer's disease or related dementias.

Not a fit: Patients who are younger than 55 or do not have a documented diagnosis of Alzheimer's disease or related dementias may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved patient-centered care and better alignment of treatment with patients' healthcare goals.

How similar studies have performed: Other studies have shown promise in improving communication and care planning for patients with serious illnesses, suggesting that this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
PATIENTS

Inclusion Criteria:

* Be cared for as an outpatient at a UW Medicine clinic
* 55 years of age or older
* Have an ICD-10 code for ADRD documented in the EHR within the prior two years

If patients are cared for in a primary care setting within UW Medicine or by a geriatrician or neurologist, only a diagnosis of ADRD is required for eligibility.

If patients have ADRD and are not followed by a primary care clinician at UW Medicine but are followed by a subspecialist, eligible patients must also have an ICD-10 code for one or more of seven chronic conditions used by the Dartmouth Atlas, relevant for the specialist they see, to ensure that goals-of care discussions are applicable for these specialists in the care of the enrolled patient. These conditions by specialist are: malignant cancer/leukemia (oncologist), chronic pulmonary disease (pulmonologist), coronary artery disease or heart failure (cardiologist), chronic liver disease (hepatologist), chronic renal disease (nephrologist), and diabetes with end-organ damage (endocrinologist).

Exclusion Criteria:

* restricted status, legal or risk management concerns
* without capacity to complete informed consent procedures and without a legal surrogate to enroll them (for the survey component or qualitative interviews)
* non-English speaking (for the survey component or qualitative interviews)
* patients of a clinician who has opted-out of the study will not be eligible for the study under the care of that clinician but may be eligible if they also receive care from another clinician in a participating clinic

FAMILY MEMBERS

Inclusion Criteria:

* Identified (via the patient or the EHR) as the person most involved in care for an eligible patient in the trial
* 18 years of age or older
* English language proficiency

Exclusion Criteria:

* legal or risk management concerns
* psychological illness or morbidity preventing completion of study materials
* physical or mental limitations preventing completion of study materials
* non-English speaking

Not all patients will have an eligible family member to enroll.

CLINICIANS

Inclusion Criteria:

* Physician or advance practice provider caring for older adults within UW Medicine clinics
* 18 years of age or older
* English language proficiency
* (Interviews) Identified as clinician of record for an enrolled patient in the trial and received a Jumpstart guide

Exclusion Criteria:

* legal or risk management concerns

Where this trial is running

Seattle, Washington and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions DementiaDementia, VascularMixed DementiasAlzheimer DiseaseHuntington DiseaseLewy Body DiseaseCreutzfeldt-Jakob SyndromeFrontotemporal Lobar Degeneration
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.