Improving GERD medication adherence using the GERDCare smartphone app

Evaluating Medication Adherence of Patients With Gastroesophageal Reflux Disease With Support of the Smartphone Application GERDCare

NA · Institute of Gastroenterology and Hepatology, Vietnam · NCT07125521

This project will test whether the GERDCare smartphone app helps adults with GERD stick to their medications, diet, and lifestyle changes over four weeks.

Quick facts

PhaseNA
Study typeInterventional
Enrollment380 (estimated)
Ages18 Years and up
SexAll
SponsorInstitute of Gastroenterology and Hepatology, Vietnam (other)
Locations1 site (Hanoi)
Trial IDNCT07125521 on ClinicalTrials.gov

What this trial studies

This is a single-center, open-label, randomized controlled trial that compares usual care with the addition of the GERDCare mobile application to support treatment adherence in adults with typical GERD symptoms. The app, developed with input from gastrointestinal experts, offers educational resources, symptom tracking, medication reminders, and direct patient–physician communication. Eligible participants are adults who own a smartphone and can use apps, and they are followed for four weeks after starting GERD treatment. Patients with acute GI emergencies, GI malignancy, severe chronic organ failure, pregnancy, significant alcohol abuse, or mental health issues affecting app use are excluded.

Who should consider this trial

Good fit: Adults (≥18 years) with typical GERD symptoms who own a smartphone and are able to use mobile applications, without major acute GI conditions or severe comorbidities, are the ideal candidates.

Not a fit: Patients with acute GI bleeding, GI cancer, severe heart/liver/kidney failure, pregnancy, active alcohol abuse, or cognitive/mental health conditions that hinder app use are unlikely to benefit from this intervention.

Why it matters

Potential benefit: If successful, the app could improve adherence to GERD treatment and reduce symptom burden and related complications.

How similar studies have performed: Mobile health applications have improved medication adherence in several chronic diseases and pilot work suggests promise for GERD, but large definitive trials in GERD remain limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ≥18 years old
* Presents with typical GERD symptoms (regurgitation, heartburn)
* Owns a smartphone and capable of using smartphone applications.

Exclusion Criteria:

* Acute GI conditions (upper GI bleeding, acute peptic ulcer…)
* GI malignancy (esophageal cancer, gastric cancer…)
* Severe chronic comorbidities (heart failure, liver failure, chronic kidney disease…)
* Pregnancy, alcohol abuse, mental health conditions impacting medication adherence or app usage

Where this trial is running

Hanoi

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: GERD, mobile apps, mobile applications, medication adherence

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.