Improving diagnosis and treatment of diabetic retinopathy in type 2 diabetes
Official title: Optimization and Evaluation of the Diagnosis and Treatment System for Diabetic Retinopathy in Type 2 Diabetes Mellitus
Run by Shanghai General Hospital, China · NCT06821399 · Data updated 2026-11-12
This study is testing a new way to spot and treat diabetic eye disease in people with type 2 diabetes by using a mix of health data and advanced technology to improve care.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years to 79 Years |
| Sex | All |
| Enrollment | 2920 (estimated) |
| Sponsor | Shanghai General Hospital, China Academic / other |
| Locations | 3 sites (Lanzhou and 2 other locations) |
| Status | Recruiting |
| Started | February 1, 2025 |
| Main results expected | August 31, 2025 |
| Study ends | July 31, 2028 |
| Registry record updated | April 23, 2026 |
| Trial ID | NCT06821399 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 20 to 79 with a diagnosis of type 2 diabetes who meet specific clinical criteria.
✕Probably not a fit
Patients with type 1 diabetes, severe underlying health conditions, or cognitive impairments may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study integrates clinical indicators and fundus image features with metabolomics to create an early warning model for diabetic retinopathy (DR) in patients with type 2 diabetes. It aims to establish a precise DR typing model based on the age of diabetes onset and the presence of diabetic macrovascular complications. A multidisciplinary approach will be employed for comprehensive management of moderate-stage DR, utilizing cloud-based patient rooms and continuous glucose monitoring to enhance patient care. The goal is to pioneer a new management model for advanced DR.
Why it matters
Potential benefit: If successful, this study could lead to earlier diagnosis and more effective management of diabetic retinopathy, potentially preserving vision in patients with type 2 diabetes.
How similar studies have gone: While similar approaches have been explored, this study's integration of metabolomics with clinical indicators represents a novel approach in the management of diabetic retinopathy.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria:
* Meets the diagnostic criteria for type 2 diabetes in the "China Type 2 Diabetes Prevention and Treatment Guidelines (2020 Edition)";
* Aged between 20 and 79 years old, without other severe underlying diseases; ③ Possesses full cognitive and literacy abilities; ④ Volunteers to participate in this study and are willing to sign an informed consent form.
Exclusion Criteria:
* Those who have been diagnosed with type 1 or other types of diabetes;
* Those with severe cardiac, pulmonary, hepatic, or renal insufficiency;
* Those with mental confusion, speech disorders, or dementia, etc.;
* Those who are unable to take care of themselves, bedridden, or have mobility impairments; ⑤ Women who are breastfeeding or pregnant;
* Those with a recent history of surgery, trauma, acute major vascular complications, or infectious diseases.
Where it's running
-
The first hosptial of lanzhou university
Lanzhou, China Recruiting -
Shanghai general hosptial
Shanghai, China Recruiting -
The forth people's hosptial of shenyang
Shenyang, China Recruiting
Study contacts
- Study coordinator: Liping Gu Liping Gu
- Email: guliping1980@126.com
- Phone: 86-13564720656
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.