Improving decision support for opioid addiction treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to enhance the EMBED clinical decision support system to improve the administration of buprenorphine for patients with opioid use disorder in emergency departments. Using a Multiphase Optimization Strategy (MOST), the study will implement a factorial trial to test various strategies, including nurse prompts and clinician reminders, to ensure adherence to standard care. The goal is to refine the usability of the decision support interface and workflow to reduce errors and improve treatment initiation for patients. The study will involve multiple phases, including preparation, optimization, and confirmatory stages.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Emergency department patient
* 18 years of age or older
* Moderate to severe opioid use disorder

Exclusion Criteria:

* Under 18 years of age
* Pregnant
* Currently receiving medication for opioid use disorder

Where it's running

• Yale New Haven Shoreline Medical Center
  Guilford, Connecticut, United States Recruiting
• Yale New Haven Hospital- St. Raphael
  New Haven, Connecticut, United States Recruiting
• Yale New Haven Hospital
  New Haven, Connecticut, United States Recruiting

Study contacts

• Principal investigator: Edward Melnick, MD, MHS — Yale University
• Study coordinator: Edward Melnick, MD, MHS
• Email: edward.melnick@yale.edu
• Phone: 203-785-4363

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• emPath platform pilot to link and keep adults with opioid use disorder in care in Durham

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• CB1 Receptors in Opioid Use Disorder Measured with a PET Radioligand

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• STORC: Training a support person plus patient navigation after birth

  We’re testing whether training a designated support person and using patient navigation after delivery helps people with opioid use disorder build recovery resources and stay in treatment.

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• Personalized Addiction Treatment Enhancement for Opioid Use Disorder

  A digital platform run by peer recovery supporters will be tested to help adults with opioid use disorder who are on buprenorphine or methadone stay in treatment and improve outcomes.

  Recruiting Rhode Island Hospital · Providence, Rhode Island · NCT07778394

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.