Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Improving cholesterol management after heart events through education

Official title: Test 2 Treat: A Randomized Implementation Trial to Improve LDL-C Management After Hospitalization for ASCVD (Atherosclerotic Cardiovascular Disease)

Run by Duke University · NCT06471036 · Data updated 2026-11-12

This study is testing if teaching doctors and patients about cholesterol management can help prevent future heart problems in people who have been hospitalized for a heart issue.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment400 (estimated)
SponsorDuke University
Academic / other
Locations1 site (Minneapolis, Minnesota)
StatusRecruiting
StartedOctober 8, 2024
Main results expectedOctober 31, 2026
Study endsFebruary 28, 2027
Registry record updatedOctober 16, 2026
Trial IDNCT06471036 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older who have been hospitalized for a Type 1 NSTEMI or STEMI and have an LDL-C level of 70 mg/dL or higher.

Probably not a fit

Patients who are unlikely to survive or continue follow-up for at least six months, such as those on hospice or with significant dementia, will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This implementation trial aims to determine if educating healthcare providers and patients about cholesterol management can prevent future heart problems in individuals hospitalized for a cardiac event. The study will assess whether training doctors improves the frequency of cholesterol checks and if a 'care champion' can assist discharged patients in achieving their cholesterol goals. Participants will complete two brief surveys over the phone, one at enrollment and another six months later, to evaluate the effectiveness of the intervention. Data will be collected from electronic health records and patient-reported outcomes to measure success.

Why it matters

Potential benefit: If successful, this approach could lead to better cholesterol management and reduced risk of future cardiac events for patients.

How similar studies have gone: Other studies have shown promise in using educational interventions to improve patient outcomes in cholesterol management, making this approach both relevant and potentially impactful.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age ≥ 18 years old
2. Admitted with Type 1 NSTEMI or STEMI, and/or percutaneous coronary revascularization
3. LDL-C level during admission ≥ 70 mg/dL
4. Primary care clinician and/or cardiologist within the health system (and with access to the same EHR) who will manage the patient in the outpatient setting

Exclusion Criteria:

1. Determined to be highly unlikely to survive and/or to continue follow-up in that health system for at least 6 months (including those on hospice or with significant dementia), as identified by site investigator
2. Underwent CABG (would therefore be discharged from surgical service)

Where it's running

  • Allina Health
    Minneapolis, Minnesota, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.