Improving access to mental health support for pregnant and postpartum women

Prevention of Perinatal Depression Among At-risk Individuals Through Integration of a Multimedia, Web-based Intervention Within the Healthcare System

NA · University of Utah · NCT06049433

This study is testing a new online mental health support program for pregnant and new moms who might be at risk for postpartum depression to see how well it works for different people.

Quick facts

PhaseNA
Study typeInterventional
Enrollment120 (estimated)
Ages18 Years and up
SexFemale
SponsorUniversity of Utah (other)
Locations1 site (Salt Lake City, Utah)
Trial IDNCT06049433 on ClinicalTrials.gov

What this trial studies

This project aims to evaluate and refine the implementation of a digital mental health intervention for postpartum depression among at-risk pregnant and postpartum women from diverse backgrounds. The study will enroll 120 participants using a randomized preference design to assess the impact of sociocultural factors on engagement and symptom trajectory. By integrating the intervention within existing maternal clinical care settings, the research seeks to optimize the feasibility and acceptability of the approach, ultimately preparing for larger multisite trials. The implementation strategies will be informed by input from key stakeholders and a Community Advisory Board throughout the project.

Who should consider this trial

Good fit: Ideal candidates include pregnant or postpartum women aged 18 and older who are at risk for perinatal depression and speak English or Spanish.

Not a fit: Patients with serious mental illnesses, substance use disorders, or severe anxiety may not benefit from this intervention.

Why it matters

Potential benefit: If successful, this intervention could significantly improve mental health outcomes for pregnant and postpartum women at risk for depression.

How similar studies have performed: Other studies have shown promise in using digital mental health interventions for postpartum depression, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18+ years of age, who at the time of screening
* Have a viable pregnancy or are postpartum (up to 1 year)
* Identified as at-risk for PD (any one of the following:
* EPDS score equal to or greater than 9 or less than 21
* History of depression/anxiety
* 2 or more significant life events)
* English- or Spanish-speaking
* Currently attending a UHealth clinic or rural public health partner clinic.

Exclusion Criteria:

* Have a substance use disorder
* Current diagnosis of serious mental illness, such as psychosis, schizophrenia, bipolar disorder, severe depression (including EPDS \> 20)
* Severe anxiety, suicidality, or currently taking any medications for a mental health condition.

Where this trial is running

Salt Lake City, Utah

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Postpartum Depression, Perinatal Depression

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.