Impact of thyroid dysfunction on liver failure outcomes
Thyoid Dysfucntion; Does it Affect the Short Term Outcome of Heptic Failure Patiens ?
This study looks at how thyroid problems affect the health and recovery of people with severe liver failure to see if treating the thyroid can help improve their outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Assiut University Academic / other |
| Locations | 1 site (Assiut) |
| Trial ID | NCT06179368 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between thyroid hormone metabolism and liver function in patients with hepatic failure. It focuses on how conditions like hypothyroidism and hepatic encephalopathy affect patient outcomes. The study will assess patients with varying degrees of liver impairment, particularly those with decompensated cirrhosis, to understand the interplay between thyroid hormones and liver health. By analyzing these interactions, the research aims to provide insights into the management of liver disease and its complications.
Who should consider this trial
Good fit: Ideal candidates for this study are patients diagnosed with hepatic failure, particularly those exhibiting signs of decompensation.
Not a fit: Patients with hyperthyroidism will not benefit from this study as they are excluded from participation.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for patients with liver failure by addressing thyroid dysfunction.
How similar studies have performed: While the relationship between thyroid function and liver disease has been explored, this specific observational approach is relatively novel and may provide new insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: - hepatic fauiure patients Exclusion Criteria: * hypethyroid patients
Where this trial is running
Assiut
- Emad Zarief Kamel Said — Assiut, Egypt (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.