Impact of switching from menthol to non-menthol cigarettes on inflammation and smoking behavior

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study examines how switching from menthol cigarettes to non-menthol cigarettes affects biomarkers of systemic inflammation and smoking behavior. A total of 68 menthol cigarette smokers will participate in a five-week study, starting with a one-week baseline period of menthol smoking, followed by four weeks of smoking non-menthol cigarettes. Blood samples will be collected at various points to analyze inflammation and tobacco exposure, while participants will also report their smoking patterns and subjective responses using a smartphone application. The study aims to provide insights into the health implications of menthol cigarette use and the effects of switching to non-menthol options.

Why it matters

Who can join: the full rules

Inclusion criteria

* Men and women between 21-85 years old
* Currently uses menthol cigarettes
* Daily smoking rate of ≥5 cigarettes/day for ≥1 year
* Currently own and regularly use an iOS/Android smartphone device able to download the LifeData application
* Able to read and communicate fluently in English

Exclusion criteria

* Currently pregnant or breastfeeding
* Actively trying to quit smoking
* Current heavy alcohol use
* Frequent use of non-menthol cigarettes, other smoking products, or illicit substances
* History of severe medical/psychiatric condition or treatment

Where it's running

• Rosalind Franklin University of Medicine and Science
  North Chicago, Illinois, United States Recruiting

Study contacts

• Principal investigator: Nancy C Jao, PhD — Rosalind Franklin University of Medicine and Science
• Study coordinator: Nancy C Jao, PhD
• Email: nancy.jao@rosalindfranklin.edu
• Phone: 847-578-8747

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.