Impact of PENG block on inflammation and mortality in hip fracture patients
Effect of PENG Block on Inflammatory Parameters and Mortality in Geriatric Patients Undergoing Hip Fracture Surgery
This study is testing if a special pain relief method called the PENG block can help older patients with hip fractures recover better and have fewer complications after surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | Ankara City Hospital Bilkent Academic / other |
| Locations | 1 site (Ankara) |
| Trial ID | NCT06795724 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of the PENG block on systemic inflammation response index (SIRI) and 30-day mortality in geriatric patients over 65 years old undergoing hip surgery. A total of 60 patients will be randomly assigned to receive either the PENG block or standard analgesia with paracetamol and tramadol. Preoperative tests for inflammatory markers will be conducted, and postoperative outcomes such as pain scores, hospital stay duration, and mortality rates will be monitored. The goal is to determine if the PENG block can improve recovery and reduce complications in this vulnerable population.
Who should consider this trial
Good fit: Ideal candidates for this study are geriatric patients over 65 years old scheduled for hip fracture surgery.
Not a fit: Patients with ASA scores of 4 and above, obesity, or those with contraindications for regional anesthesia techniques may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to reduced inflammation and lower mortality rates in elderly patients undergoing hip fracture surgery.
How similar studies have performed: While the specific application of the PENG block in this context is novel, similar regional anesthesia techniques have shown promise in reducing postoperative complications in other studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ASA 1-2-3 score * Hip Fracture Surgery Exclusion Criteria: * Refusal to participate in the study * ASA score of 4 and above * Obesity (BMI \>40) * Failure of spinal block * Switching to general anesthesia * Patients undergoing revision surgery * Patients with multitrauma * Patients with old fractures (\>3 weeks) * Patients receiving preoperative and intraoperative sedation * Patients with active malignancy receiving RT, KT * Patients with active infection, patients receiving antibiotic treatment * Patients with contraindications for regional anesthesia techniques * Patients receiving chronic treatment with steroids or immunosuppressants * Patients using anti-inflammatory drugs
Where this trial is running
Ankara
- Ankara Bilkent City Hospital — Ankara, Turkey (Recruiting)
Study contacts
- Principal investigator: burak nalbant — Ankara City Hospital Bilkent
- Study coordinator: burak nalbant
- Email: buraknalbant@gmail.com
- Phone: 05332231990
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.