Clinical trial Recruiting at 1 site Observational Ages 18 and up

Impact of Increased Physical Activity on Rheumatoid Arthritis Outcomes

Official title: Predictive Utility of a Short-Term Improvement in Objectively Measured Physical Activity in Rheumatoid Arthritis Patients Initiating Biologics: A Prospective Cohort Study

Run by Esbjerg Hospital - University Hospital of Southern Denmark · NCT06289114 · Data updated 2026-11-12

This study is trying to see if increasing physical activity after starting a new RA treatment helps people feel better and how fibromyalgia might change that.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment100 (estimated)
SponsorEsbjerg Hospital - University Hospital of Southern Denmark
Academic / other
Locations1 site (Esbjerg)
StatusRecruiting
StartedSeptember 1, 2023
Main results expectedSeptember 1, 2025
Study endsSeptember 1, 2025
Registry record updatedMarch 17, 2025
Trial IDNCT06289114 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults over 18 years old diagnosed with rheumatoid arthritis who are starting treatment with a biological agent.

Probably not a fit

Patients who are physically impaired or unable to participate in physical activity due to reliance on walking assistance devices may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the relationship between short-term improvements in physical activity and disease activity in patients with rheumatoid arthritis (RA). It will compare the outcomes of RA patients who experience an immediate increase in physical activity after one week of biological treatment to those who do not, over a 12-week period. Additionally, the study will explore how the presence of fibromyalgia affects this relationship. The methodology includes a prospective cohort design utilizing accelerometry to objectively measure physical activity levels.

Why it matters

Potential benefit: If successful, this study could provide insights into how increasing physical activity may improve disease outcomes for patients with rheumatoid arthritis.

How similar studies have gone: Previous studies have shown mixed results regarding the relationship between physical activity and disease activity in rheumatoid arthritis, indicating that this approach is both relevant and necessary for further exploration.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with RA (\> 18 years of age)
* Patients who are to be treated with a biological agent
* Patients who can read and understand Danish

Exclusion Criteria:

* Patients who are physically impaired (patients depending on assistance devices for walking)
* Pregnancy
* Patients who have received corticosteroids two weeks prior to and during the period of the movement measurement
* Patients who by virtue of illiteracy or cognitive impairment, are unable to complete the questionnaire.

Where it's running

  • Esbjerg Hospital
    Esbjerg, Denmark
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.