Impact of Increased Physical Activity on Rheumatoid Arthritis Outcomes
Predictive Utility of a Short-Term Improvement in Objectively Measured Physical Activity in Rheumatoid Arthritis Patients Initiating Biologics: A Prospective Cohort Study
This study is trying to see if increasing physical activity after starting a new RA treatment helps people feel better and how fibromyalgia might change that.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Esbjerg Hospital - University Hospital of Southern Denmark Academic / other |
| Locations | 1 site (Esbjerg) |
| Trial ID | NCT06289114 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the relationship between short-term improvements in physical activity and disease activity in patients with rheumatoid arthritis (RA). It will compare the outcomes of RA patients who experience an immediate increase in physical activity after one week of biological treatment to those who do not, over a 12-week period. Additionally, the study will explore how the presence of fibromyalgia affects this relationship. The methodology includes a prospective cohort design utilizing accelerometry to objectively measure physical activity levels.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old diagnosed with rheumatoid arthritis who are starting treatment with a biological agent.
Not a fit: Patients who are physically impaired or unable to participate in physical activity due to reliance on walking assistance devices may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into how increasing physical activity may improve disease outcomes for patients with rheumatoid arthritis.
How similar studies have performed: Previous studies have shown mixed results regarding the relationship between physical activity and disease activity in rheumatoid arthritis, indicating that this approach is both relevant and necessary for further exploration.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with RA (\> 18 years of age) * Patients who are to be treated with a biological agent * Patients who can read and understand Danish Exclusion Criteria: * Patients who are physically impaired (patients depending on assistance devices for walking) * Pregnancy * Patients who have received corticosteroids two weeks prior to and during the period of the movement measurement * Patients who by virtue of illiteracy or cognitive impairment, are unable to complete the questionnaire.
Where this trial is running
Esbjerg
- Esbjerg Hospital — Esbjerg, Denmark (Recruiting)
Study contacts
- Study coordinator: Philip R Lage-Hansen, MD
- Email: philip.rask.lage-hansen3@rsyd.dk
- Phone: +4530114582
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.