Impact of Hyperglycemia on Outcomes in Acute Stroke Patients
One Year Mortality and Morbidity Outcome With Hyperglycemia Among Acute Cerebrovascular Accident Patients in Emergency Department: A Prospective Cohort Study
This study is trying to see how high blood sugar affects the recovery and health of people who have had a stroke.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 46 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Institute of medicine, Maharagjung medical campus Academic / other |
| Locations | 2 sites (Kathmandu, Bagmati and 1 other locations) |
| Trial ID | NCT06560983 on ClinicalTrials.gov |
What this trial studies
This observational cohort study investigates how hyperglycemia affects both short- and long-term outcomes in patients who present to the emergency department with acute cerebrovascular accidents (CVAs). Conducted at Tribhuvan University Teaching Hospital, the study employs a systematic random sampling method to ensure a representative sample of 60 participants, half with hyperglycemia and half with normal glycemic levels. The research adheres to rigorous methodological standards, including the STROBE guidelines, to provide high-quality evidence on the relationship between hyperglycemia and mortality/morbidity rates in acute stroke patients. The findings aim to fill a critical knowledge gap regarding the long-term consequences of hyperglycemia in this patient population.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals over 40 years old who exhibit BEFAST-positive symptoms and have confirmed acute stroke through CT imaging.
Not a fit: Patients presenting with hypoglycemia, transient ischemic attacks, or other conditions mimicking stroke symptoms may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for acute stroke patients with hyperglycemia, potentially reducing mortality and morbidity rates.
How similar studies have performed: While the relationship between hyperglycemia and stroke outcomes has been explored in other studies, this specific cohort approach is novel and aims to provide new insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Individuals exhibiting BEFAST-positive symptoms - meeting at least one of the criteria within 24 hours of symptom onset. * Confirmation of acute stroke through CT imaging. * Participants aged over 40 years. Exclusion Criteria: * Patients presenting with hypoglycemia * Transient Ischemic Attack (TIA). * Subdural hematoma cases. * Subarachnoid hemorrhage cases. * Diabetic Ketoacidosis. * Conditions mimicking stroke symptoms (e.g., sepsis, metabolic derangement, space-occupying lesions, hepatic encephalopathy). * History of bedridden patients. * Acute-on-chronic stroke cases. * Patients requiring assistance in daily activities. * History of trauma preceding the stroke.
Where this trial is running
Kathmandu, Bagmati and 1 other locations
- Bibek Rajbhandari — Kathmandu, Bagmati, Nepal (Not_yet_recruiting)
- Bibek Rajbhandari — Kathmandu, Bagmati, Nepal (Recruiting)
Study contacts
- Study coordinator: Bibek Rajbhandari, masters
- Email: bibekrajbhandarimg@gmail.com
- Phone: 9851281884
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.