Impact of firefighting training on health risks

Effect on Markers of Cardiovascular, Reproductive and Cancer Risk From Firefighting Activities - a Study Under Different Training Methods

Not applicable Interventional National Research Centre for the Working Environment, Denmark · NCT05753254

This study tests how different firefighting training conditions affect the health risks related to heart health, reproductive health, and cancer for firefighters.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment35 (estimated)
Ages18 Years and up
SexAll
SponsorNational Research Centre for the Working Environment, Denmark Government
Locations2 sites (Copenhagen and 1 other locations)
Trial IDNCT05753254 on ClinicalTrials.gov

What this trial studies

This study investigates the health effects of different firefighting training conditions on cardiovascular, reproductive, and cancer risk markers. It employs a crossover design where participants undergo training sessions under varying conditions: no fire, wood fire, and gas fire. The study aims to assess the individual contributions of stressors such as heat, smoke, and soot on health outcomes. Participants will be monitored for biomarkers related to cardiovascular health, reproductive health, and cancer risk during these training exercises.

Who should consider this trial

Good fit: Ideal candidates for this study are male and female conscripts enrolled in a Rescue Specialist Educational course who are legally competent and meet specific health criteria.

Not a fit: Patients who are current smokers, pregnant, on prescribed medication, or have a BMI outside the specified range may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved health and safety protocols for firefighters, reducing their risk of cardiovascular disease, infertility, and cancer.

How similar studies have performed: While there have been studies on occupational health risks among firefighters, this specific approach of assessing different training conditions is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
The participants will be volunteers (both males and females) recruited among conscripts in training in a desirable involved group up to 35 individuals.

Inclusion Criteria:

* legally competent,
* conscript subjects following a Rescue Specialist Educational course

Exclusion Criteria:

* current smoking status,
* pregnancy,
* on prescribed medication,
* body mass index (BMI) bellow 19 or over 30,
* alcohol or drug abuse.

Where this trial is running

Copenhagen and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Reactive HyperemiaMicro RNAHeart Rate VariabilityDNA Strand BreaksOxidative StressHeat StressComet assay8-oxodG
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.