Impact of cognitive difficulties on daily life in Myasthenia Gravis patients
Cognitive Functioning in People with Myasthenia Graivs: Impact on Daily Life Activities, Work, Disability and Quality of Life
This study looks at how cognitive difficulties affect daily life for people with Myasthenia Gravis and whether these challenges vary based on the type of MG and treatments they receive.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Ages | 18 Years to 99 Years |
| Sex | All |
| Sponsor | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta Academic / other |
| Locations | 1 site (Milano) |
| Trial ID | NCT06718855 on ClinicalTrials.gov |
What this trial studies
This observational study aims to estimate the prevalence of cognitive difficulties in patients with Myasthenia Gravis (MG) treated at the Besta Institute. It will assess how these cognitive challenges relate to work impairment, limitations in daily activities, and overall quality of life. The study will also explore variations in cognitive impairment based on different types of MG, antibody profiles, and pharmacological treatments. Cognitive functioning will be measured using various standardized assessments.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-99 with a diagnosis of Myasthenia Gravis who can understand Italian.
Not a fit: Patients with psychiatric comorbidities, those under mechanical ventilation, or residing in nursing homes may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of cognitive impairment in MG patients, leading to improved management strategies and support.
How similar studies have performed: While previous literature has shown mixed results regarding cognitive impairment in MG, this study aims to clarify these findings, making it a novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with MG, * followed-up at Besta institute * aged 18-99, * able to understand Italian language; Exclusion Criteria: * psychiatric comorbidies of psychotic nature; * do not accept to participate on a voluntary basis; * patients who should be excluded based on physician's judgement; * patients who live in a nursing home for aged or disabled persons; * respiratory impairment (patients under mechanical ventilation)
Where this trial is running
Milano
- Fondazione IRCCS Istituto Neurologico Carlo Besta — Milano, Italy (Recruiting)
Study contacts
- Study coordinator: Alessia Marcassoli, MS
- Email: alessia.marcassoli@istituto-besta.it
- Phone: +39 02 2394
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.