Immediate implant placement with titanium mesh and xenograft versus collagen membrane for buccal bone defects in the front upper jaw

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This parallel-arm randomized trial compares two approaches to immediate implant placement in patients with buccal bone defects in the anterior maxilla. Group A uses xenograft grafting covered by a titanium mesh and collagen membrane, while Group B uses xenograft grafting covered by a collagen membrane alone. Outcomes include buccal bone thickness and soft tissue thickness measured at 6 and 12 months, along with postoperative pain and swelling documented for the first two weeks after surgery. Participants are adults aged 21–50, ASA I, with at least one remaining root or badly decayed tooth in the anterior maxilla and deficient buccal bone, and will be followed to assess healing and implant stability. Data will be analyzed to determine if the mesh-assisted approach provides a thicker buccal plate compared with the membrane-alone method.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients who have at least one remaining root or badly decayed tooth in anterior maxilla.
2. Systemically free patients (American Society of Anesthesiologists I; ASA I)
3. Patients aged from 21 to 50 years old
4. Buccal bone partial deficiency (extraction socket type II)
5. Good oral hygiene
6. Accepts the follow-up period (cooperative patients)
7. Patient accepts to provides an informed consent

Exclusion Criteria:

1. Patients with habits that may jeopardize the implant longevity and affect the results of the study such as parafunctional habits such as bruxism
2. Smokers
3. Pregnant and lactating females

Where it's running

• Faculty of oral & dental Medicine,Misr international University
  Cairo, Heliopolis - Cairo, Egypt Recruiting

Study contacts

• Principal investigator: ahmed H Farid, Masters — Assistant lecturer
• Study coordinator: Hani El Nahas, PhD
• Email: zeinab.hafez@miuegypt.edu.eg
• Phone: +201221334637

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.