Rebuilding upper jaw ridge using retromolar bone blocks with or without a collagen membrane
Reconstruction of Horizontally Deficient Atrophic Maxillary Ridges Using Retromolar Blocks With and Without Coverage Using Collagen Membrane (Randomized Clinical Trials)
This will test whether putting a collagen membrane over an onlay bone block and particulate bone in the upper jaw helps people who need ridge rebuilding get more bone.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 20 Years to 40 Years |
| Sex | All |
| Sponsor | Cairo University Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06900933 on ClinicalTrials.gov |
What this trial studies
This interventional comparison enrolls patients needing maxillary ridge augmentation and compares two surgical techniques: onlay retromolar bone block with particulate bone covered by a resorbable collagen membrane versus the same onlay block without a membrane. Bone quantity after healing will be measured to see if the membrane preserves space and supports graft integration. The trial excludes patients with factors that impair healing such as heavy smoking, uncontrolled diabetes, prior head and neck radiotherapy, or active bone disease. Procedures and follow-up visits are performed at the Faculty of Dentistry, Cairo University using standard surgical and postoperative care.
Who should consider this trial
Good fit: Adults missing at least one maxillary tooth with residual alveolar bone height ≥8 mm and alveolar width ≤5 mm who can attend surgical and follow-up visits in Cairo are ideal candidates.
Not a fit: People who heavily smoke, have uncontrolled metabolic or bone disease, prior head/neck radiation, active infection, or are pregnant are unlikely to benefit or be eligible.
Why it matters
Potential benefit: If successful, the approach could increase bone volume at graft sites and improve the chances for stable dental implants.
How similar studies have performed: Collagen membranes are widely used in guided bone regeneration and have shown benefit for preserving grafts, although their specific use over onlay retromolar blocks has less extensive published evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with maxillary residual alveolar bone height not less than 8 mm. * Alveolar bone width from less than or equal 5 mm. * Both genders. * At least missing single tooth. * Previous Failed Implants. * Previous Failed Grafting. Exclusion Criteria: * • Heavy smokers more than 20 cigarettes per day. * Patients with alcohol abuse * Patients with narcotic abuse. * Patients with bone disease that may affect normal healing, example; hyperparathyroidism. * Patients had radiotherapy and chemotherapy in head and neck. * Patients had neoplasms in sites to be grafted. * Patients with Metabolic diseases uncontrolled diabetic patients, Glycated hemoglobin (Hb A1c) more than 7 mg\\dl. * Pregnant females. * Patients with Para functional habits, apprehensive and non-cooperative. * Bone pathology related to the site to be grafted. * Psychological problems, stress situation (socially or professionally), emotional instability, and unrealistic patients' expectations. * Intraoral soft and hard tissue pathology. * Systemic condition that contraindicate implant placement. * Under the age of 18 years.
Where this trial is running
Cairo
- Faculty of Dentistry Cairo University — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Mohannad A. Ismail, MSc.
- Email: mohannadahmed@hotmail.com
- Phone: 01222968444
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.