Identifying triggers and progression of heart failure
Heart Failure-USB: Prediction and Progression
This study looks at patients with heart failure to see what causes it and how it gets worse, while also testing if digoxin can help those whose heart failure is triggered by fast heartbeats.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 6000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Basel, Switzerland Academic / other |
| Locations | 1 site (Basel) |
| Trial ID | NCT04000061 on ClinicalTrials.gov |
What this trial studies
This observational study aims to analyze data from patients hospitalized with acute coronary syndrome and acute heart failure between 2010 and 2023. It focuses on identifying the triggers for heart failure development and the factors driving its progression, as well as understanding the underlying cardiac disease phenotype. Additionally, a subgroup of patients will be evaluated for the efficacy and safety of digoxin in cases of acute heart failure triggered by tachyarrhythmia. The study utilizes medical chart reviews and data exports for comprehensive analysis.
Who should consider this trial
Good fit: Ideal candidates include patients who were hospitalized with acute coronary syndrome or acute heart failure.
Not a fit: Patients who have opted out of the scientific use of their clinical data will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the prediction and management of heart failure, leading to improved patient outcomes.
How similar studies have performed: Other studies have shown success in identifying risk factors and predictors for heart failure, making this approach promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients hospitalized with a primary diagnosis of ACS * Patients hospitalized with a primary or secondary diagnosis of AHF Exclusion Criteria: * Existence of a documented statement of the patient against the scientific use of clinical data
Where this trial is running
Basel
- Cardiology, University Hospital Basel — Basel, Switzerland (Recruiting)
Study contacts
- Principal investigator: Christian Müller, Prof. Dr. — Cardiology University Hospital Basel
- Study coordinator: Christian Müller, Prof. Dr.
- Email: Christian.mueller@usb.ch
- Phone: 0041 6132 86 549
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.