Identifying stroke risk in heart surgery patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to determine if patients at risk of forming blood clots, which can lead to strokes, can be identified through electrocardiogram analysis. Patients scheduled for elective heart surgery will have their left atrial appendage closed, a common procedure for those with atrial fibrillation. During surgery, tissue from the appendage will be collected for analysis alongside blood samples and ECG data. The study will investigate thrombosis factors and inflammatory markers to better understand the arrhythmogenic and thrombogenic substrates.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* signed informed consent AND
* planned any open-heart surgery:

  * CABG
  * valve repair or replacement
  * aorta surgery
  * any combination of the above

Exclusion Criteria:

* current endocarditis
* follow-up not possible

Where it's running

• Rigshospitalet
  Copenhagen, Denmark Recruiting

Study contacts

• Study coordinator: Helena DOMINGUEZ, MD, PhD
• Email: mdom0002@regionh.dk
• Phone: 4522989343

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.