Identifying risk factors for cough after lung surgery

A Prospective Cohort Study on Risk Factors for Postoperative Cough in Patients Undergoing Thoracoscopic Lung Resection

Observational Hematology department of the 920th hospital · NCT06476249

This study is trying to find out what causes coughing after lung surgery in people with lung cancer to help improve their recovery.

Quick facts

Study typeObservational
Enrollment1000 (estimated)
Ages18 Years to 70 Years
SexAll
SponsorHematology department of the 920th hospital Academic / other
Locations1 site (Kunming, Yunnan)
Trial IDNCT06476249 on ClinicalTrials.gov

What this trial studies

This observational study aims to investigate the risk factors associated with postoperative cough in patients undergoing thoracoscopic lung resection for lung cancer. It will involve a cohort of 1000 participants over three years, who will be divided into two groups based on the presence or absence of cough symptoms at admission. The study will assess the severity and trajectory of cough, as well as the physiological and social impacts of cough on patients post-surgery. The findings could help improve postoperative care and management for lung cancer patients.

Who should consider this trial

Good fit: Ideal candidates are patients aged 18 to 70 who are undergoing video-assisted thoracoscopic pneumonectomy for lung cancer.

Not a fit: Patients with pre-existing cough conditions, distant metastasis, or other significant systemic diseases may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to better management strategies for postoperative cough, improving recovery and quality of life for lung cancer patients.

How similar studies have performed: While there have been studies on postoperative complications in lung surgery, this specific focus on cough as a postoperative symptom is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

● Patients aged 18 years or older and less than or equal to 70 years of age who underwent surgery with video-assisted thoracoscopic pneumonectomy.

Exclusion Criteria:

* Pre-existing cough before surgery (e.g. asthma, taking ACEI Drugs, etc.)
* Distant metastasis of tumor
* Combined pregnancy or breastfeeding
* Combined with other systemic major diseases (such as malignant swelling, chronic liver insufficiency, chronic renal insufficiency, etc.)
* Suffering from mental illness
* Refusal of follow-up or incomplete clinical information
* Poor compliance and other groups considered by the investigator not suitable for inclusion

Where this trial is running

Kunming, Yunnan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Lung Cancercough after pulmonary resectionthoracoscopic lung resection
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.