Identifying risk factors for complications after ovarian cancer surgery
Identification of Risk Factors and Construction of Prediction Model for Postoperative Intestinal Anastomotic Leakage in Ovarian Cancer
This study is trying to find out what factors might lead to complications after surgery for ovarian cancer, specifically looking at how to prevent issues with the intestines during recovery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Sex | Female |
| Sponsor | Zhongda Hospital Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Nanjing, Jiangsu) |
| Trial ID | NCT06458361 on ClinicalTrials.gov |
What this trial studies
This observational study aims to identify risk factors associated with postoperative intestinal anastomotic leakage in patients undergoing tumor cytoreductive surgery for ovarian cancer. By analyzing a multicenter, retrospective cohort, the study seeks to construct a prediction model that can aid in perioperative risk assessment. The focus is on understanding how surgical techniques and patient characteristics influence the likelihood of anastomotic leakage, which can significantly impact postoperative recovery and overall survival. The findings could lead to improved clinical decision-making and better management of patients at risk for this serious complication.
Who should consider this trial
Good fit: Ideal candidates for this study are patients diagnosed with primary ovarian, fallopian tube, or peritoneal cancer who are undergoing tumor cytoreductive surgery with colorectal resection.
Not a fit: Patients with a history of other malignant tumors or serious comorbidities related to other organs may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance postoperative outcomes and quality of life for patients by enabling timely interventions to prevent anastomotic leakage.
How similar studies have performed: Other studies have explored risk factors for surgical complications in cancer surgeries, indicating that this approach has potential but may also include novel aspects specific to ovarian cancer.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients with postoperative pathological diagnosis of primary ovarian, fallopian tube or peritoneal cancer 2. Patients undergoing tumour cytoreductive surgery combined with colorectal resection and stage I intestinal anastomosis 3. No history of other malignant tumours 4. Complete case data Exclusion Criteria: 1. Previous combination of malignant tumours of other organs 2. Comorbidities with serious diseases related to other organs 3. Patients undergoing secondary tumour cytoreduction
Where this trial is running
Nanjing, Jiangsu
- Zhongda Hospital — Nanjing, Jiangsu, China (Recruiting)
Study contacts
- Study coordinator: Yang Shen, M.D
- Email: shenyang@seu.edu.cn
- Phone: 025-83262742
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.