Identifying cognitive biomarkers for pain and depression

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to explore the feasibility of identifying cognitive biomarkers that are applicable across different conditions, specifically chronic pain and depression. It will involve 15 healthy controls and 15 participants from each of the disease groups, utilizing task-based fMRI and transcranial magnetic stimulation (TMS) to assess cognitive function. The study will measure changes in dorsolateral prefrontal cortex (DLPFC) activity before and after TMS priming, alongside behavioral assessments and EEG monitoring. The goal is to better understand cognitive dysfunction and its underlying mechanisms in these populations.

Why it matters

Who can join: the full rules

Arm 1, healthy controls:

Inclusion Criteria:

* Have access to the online study platform.

Exclusion Criteria:

* under 18, non-English speaking

Arm 2: pain and depression:

Inclusion Criteria:

* Pain or depression

Exclusion Criteria:

* pregnant women

Where it's running

• University of Minnesota
  Minneapolis, Minnesota, United States Recruiting

Study contacts

• Study coordinator: David Darrow
• Email: hdlab@umn.edu
• Phone: (612) 624-6666

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.