Identifying biomarkers in kidney disease before and after transplantation
Diagnostic and PROgnostic BIOmarkers Before and After Kidney Transplantation
This study is trying to find specific markers in urine, blood, and tissue that can help doctors better diagnose and predict kidney disease before and after a transplant.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Assistance Publique - Hôpitaux de Paris Academic / other |
| Locations | 1 site (Créteil) |
| Trial ID | NCT06810258 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on identifying urinary, blood, and tissue biomarkers associated with kidney diseases, particularly in the context of kidney transplantation. By analyzing samples collected during native kidney biopsies and renal graft biopsies, the study aims to establish biomarkers that can aid in the diagnosis and prognosis of kidney conditions. The goal is to improve long-term kidney graft survival by enabling earlier and more accurate diagnosis compared to traditional biopsy methods, which are invasive and limited in scope.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 years old who are hospitalized for a renal biopsy or kidney transplantation and can provide informed consent.
Not a fit: Patients who are pregnant, breastfeeding, under legal protection, or unable to give consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved long-term survival rates for kidney transplants by allowing for earlier and more precise interventions.
How similar studies have performed: Other studies have shown promise in using biomarkers for kidney disease diagnosis, but this specific approach remains novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient hospitalised for renal biopsy of a native kidney or for renal transplantation * Age \>18 years * Informed and consented * Covered by a social security scheme Exclusion criteria: * Patients under guardianship, conservatorship or legal protection * Pregnant or breastfeeding * Patient deprived of liberty * Patients of legal age who are unable to give consent
Where this trial is running
Créteil
- Hôpital Henri Mondor — Créteil, France (Recruiting)
Study contacts
- Study coordinator: Marie Dr MATIGNON, MD, PhD
- Email: marie.matignon@aphp.fr
- Phone: 01-49-81-44-51
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.