HPV prevention support for U.S. Vietnamese families
Official title: Applying the Multiphase Optimization Strategy to Develop and Test a Culturally-Relevant Digital Health Intervention Targeting HPV Vaccination Among U.S. Vietnamese
Run by Northwestern University · NCT07637630 · Data updated 2026-11-12
This pilot tests four digital components to help U.S. Vietnamese parents decide to vaccinate their adolescents against HPV.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 96 (estimated) |
| Sponsor | Northwestern University Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Status | Recruiting |
| Started | June 5, 2026 |
| Main results expected | June 30, 2029 |
| Study ends | June 30, 2029 |
| Registry record updated | November 9, 2026 |
| Trial ID | NCT07637630 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Parents of unvaccinated adolescents (ages 9-18) who self-identify as U.S. Vietnamese and are fluent in Vietnamese or English, and who have lived in the U.S. for at least 12 months.
✕Probably not a fit
Parents not seeking to vaccinate or without access to the digital components may not experience direct benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project uses the MOST framework to pilot four digital components—expert video, self-persuasion, narrative storytelling, and motivational interviewing—aimed at increasing HPV vaccination among unvaccinated adolescents with U.S. Vietnamese parents. Ninety-six eligible parents will be randomized to receive 0 to 4 components, with feasibility (reach, retention, adherence) and acceptability (usability, satisfaction, perceived relevance) as primary outcomes. Secondary aims explore how each component affects initial vaccination decisions and related psychosocial mediators. Participants will be recruited online, via community organizations, social media, and in-person events, and screened for eligibility. The lead institution is Northwestern University, with the National Cancer Institute as a collaborator, and the study will be conducted at Northwestern in Chicago, IL.
Why it matters
Potential benefit: If successful, the approach could improve HPV vaccination rates among adolescents in the U.S. Vietnamese community by offering targeted, culturally relevant digital supports.
How similar studies have gone: Prior studies in digital health and behavioral frameworks have shown promise for increasing vaccination intentions, but this specific MOST-based, multi-component HPV-vaccine intervention in the U.S. Vietnamese population is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Self-identify as U.S. Vietnamese. * Are the parent of a youth ages 9-18 who have not initiated the HPV vaccine series. Only one parent per household will be able to participate. * Have lived in the U.S. for 12 months or more. Exclusion Criteria: * Planning to move out of the U.S. within the next 6 months. * Not fluent in either spoken and written Vietnamese or spoken and written English. * Inability to provide informed consent.
Where it's running
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Northwestern University
Chicago, Illinois, United States Recruiting
Study contacts
- Principal investigator: Milkie Vu, PhD — Northwestern University
- Study coordinator: Milkie Vu
- Email: milkie.vu@northwestern.edu
- Phone: 312-503-6592
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.