Culturally targeted messaging to increase HPV vaccination for daughters in Flint

Culturally Targeted Messaging and Parental Receptivity to the Human Papillomavirus Vaccine

Not applicable Interventional Michigan State University · NCT07301905

This project will test whether culturally targeted messages help African American parents in Flint be more willing to vaccinate their vaccine-age daughters against HPV.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment265 (estimated)
Ages18 Years and up
SexAll
SponsorMichigan State University Academic / other
Locations1 site (Flint, Michigan)
Trial IDNCT07301905 on ClinicalTrials.gov

What this trial studies

This interventional trial compares culturally targeted HPV vaccine messages, general education-only messages, and no messaging to see which approach increases parents' intentions to vaccinate their daughters. Parents will view one of the message types and immediately report their vaccination intentions, and researchers will follow up six months later to record whether HPV vaccination was initiated. The study also measures activation of racism-related thinking and medical mistrust to understand how these factors influence message effectiveness. Messages were developed in collaboration with community members and a local health educator to reflect local cultural context.

Who should consider this trial

Good fit: Ideal candidates are Black/African American or White parents in Flint who have at least one daughter aged 8–17 who has not received any doses of the HPV vaccine.

Not a fit: Parents whose daughters have already started the HPV vaccine series, who do not identify as Black/African American or White, or who cannot participate in the Flint-based protocol are unlikely to benefit from this effort.

Why it matters

Potential benefit: If successful, culturally targeted messaging could increase HPV vaccine uptake among African American girls and help reduce cervical cancer disparities.

How similar studies have performed: Previous work on culturally tailored vaccine messaging has sometimes improved vaccine intentions and uptake in minority groups, but results have been mixed and often depend on local context.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Identify as Black/African American or White/Caucasian
* Have at least one daughter who is between 8-17 years of age, who is not currently pregnant, and who has not received any doses of the HPV vaccine

Exclusion Criteria:

* N/A

Where this trial is running

Flint, Michigan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HPV Vaccination
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.