Ho:YAG versus thulium fiber laser for mini-PCNL with the ClearPetra suction sheath

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Mini‑PCNL uses a reduced‑diameter sheath and depends on laser fragmentation to clear stones; Ho:YAG has been the long‑standing standard while thulium fiber laser (TFL) is a newer alternative. The ClearPetra vacuum‑assisted renal access sheath (VA‑RAS) adds irrigation and suction during mini‑PCNL and may change how each laser performs. This interventional trial compares outcomes when mini‑PCNL with VA‑RAS is performed using high‑power Ho:YAG with MOSES technology versus TFL. Key outcomes include stone clearance, operative time, need for additional procedures, and perioperative complications in adult patients treated at a single center.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Males or females over 18 years of age
2. Patients with kidney stones, with stone burden larger than 15 mm.
3. Patients undergoing new percutaneous access with primary, supine, unilateral mini-PCNL.

   Exclusion Criteria:
4. Simultaneous use of more than 1 laser platform or other form of fragmentation (e.g., ultrasonic).
5. Patients undergoing simultaneous treatment of contralateral kidney stones during the same procedure.
6. Patients undergoing simultaneous treatment of ureteral stones during the same procedure.
7. Pregnant patients.
8. Presence of genitourinary anatomical abnormalities.
9. Uncorrected coagulopathy.
10. External urinary catheters.
11. Immunosuppressed patients.
12. Non-elective procedures.

Where it's running

• University of Kansas Medical Center
  Kansas City, Kansas, United States Recruiting

Study contacts

• Principal investigator: Bristol Whiles, MD — University of Kansas Medical Center
• Study coordinator: Jane Ledesma
• Email: jledesma2@kumc.edu
• Phone: 913-588-8721

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.