How well a peptide supplement helps resistance training grow muscle

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Healthy adults aged 18–35 will do a structured resistance-training program for several weeks while receiving either a daily peptide supplement or a placebo. The study will measure changes in muscle size and strength, and collect blood and muscle samples to understand how the supplement may influence muscle protein synthesis and related processes. Researchers will use DEXA scans and muscle strength tests to track adaptations over time. Participation requires no current structured training and adherence to the study protocol, with safety monitored throughout.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Aged 18-35 years
* Body Mass Index (BMI, calculated by research team based on height and weight) between 18.5-27.4 kg.m-2
* Meeting UK physical activity guidelines (150 mins moderate or 75 mins vigorous activity/week)
* Not currently participating in structured progressive resistance exercise training or have regularly participated in previous 6 months
* In good health, being free from disease or conditions (e.g., Type-II diabetes, hyper/hypothyroidism, irritable bowel syndrome, polycystic ovary syndrome) which influence skeletal muscle metabolism or digestion (self-declared)

Exclusion Criteria:

* Have an allergy to ingredients of the supplement or placebo supplement (e.g., legume/bean, corn allergies)
* Have used dietary supplements which are known to affect skeletal muscle recovery and exercise adaptations (e.g., creatine) within the previous month
* Are a smoker/vaper or have a history of smoking/vaping in previous year
* Have a respiratory condition (e.g., asthma, chronic obstructive pulmonary disease)
* Using hormone therapy (not including birth control), anabolic steroids, or recreational drugs
* Are pregnant or currently breastfeeding
* Are currently trying to conceive a child
* Have any injury or body weakness which prevents participation in full body resistance exercise
* Have a known allergy to lidocaine

Where it's running

• School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham
  Birmingham, Birmingham, United Kingdom Recruiting

Study contacts

• Principal investigator: Nathan Hodson — University of Birmingham
• Study coordinator: Nathan Hodson, PhD
• Email: n.w.hodson@bham.ac.uk
• Phone: 07526146514

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.