Clinical trial Recruiting at 1 site Interventional Ages 18 and up

How to talk about vaccines: does different communication help people decide to get vaccinated?

Official title: Effectiveness Assessment of Communication Interventions to Improve Vaccination Knowledge and Acceptance

Run by Charite University, Berlin, Germany · NCT07921121 · Data updated 2026-11-12

This online randomized trial tests whether specific communication formats can improve knowledge and willingness to get vaccinated for TBE (Germany) or yellow fever (Colombia).

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment1524 (estimated)
SponsorCharite University, Berlin, Germany
Academic / other
Locations1 site (Berlin, State of Berlin)
StatusRecruiting
StartedOctober 23, 2026
Main results expectedNovember 2026
Study endsNovember 2026
Registry record updatedNovember 6, 2026
Trial IDNCT07921121 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

German citizens eligible for TBE vaccination information or Colombian citizens eligible for yellow fever vaccination information who are willing to participate online.

Probably not a fit

Participants who already have high confidence and knowledge about these vaccines may see little new benefit from the materials.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study uses an online randomized controlled design to test three approaches for informing people about vaccination: a control condition, an information website, and a slideshow/carousel format. Participants are adults from Germany or Colombia who are asked about their vaccination status and risk perceptions, then randomly assigned to one of the three arms. The aim is to see if tailored communication can increase informed vaccination decisions regarding TBE or yellow fever vaccines. The project builds on prior qualitative and quantitative work conducted in Europe and South America and involves collaboration with a Dutch research institute and a Colombian research center.

Why it matters

Potential benefit: If successful, the study could provide evidence on how best to present vaccine information to improve informed decision-making and vaccination uptake.

How similar studies have gone: Previous exploratory studies in Germany and Colombia informed the current online trial, suggesting potential for improved knowledge and willingness with optimized communication.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* German citizens
* Colombian citizens

Exclusion Criteria:

* Citizens of all other countries

Where it's running

  • Charité - Universitätsmedizin Berlin, Berlin-Mitte
    Berlin, State of Berlin, Germany
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.