Clinical trial Recruiting at 1 site Observational Ages 18 and up

AI-generated treatment recommendations for precision oncology

Official title: Eine Nichtunterlegenheitsstudie zu KI-generierten, Personalisierten Therapieempfehlungen für Die Präzisionsmedizin (AI-PRIME)

Run by Charite University, Berlin, Germany · NCT07897110 · Data updated 2026-11-12

A non-interventional study tests whether AI-generated treatment options for advanced solid tumors align with what doctors would personally recommend.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment191 (estimated)
SponsorCharite University, Berlin, Germany
Academic / other
Locations1 site (Berlin)
StatusRecruiting
StartedSeptember 1, 2026
Main results expectedApril 1, 2027
Study endsJuly 1, 2027
Registry record updatedNovember 5, 2026
Trial IDNCT07897110 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (≥18 years) with advanced solid tumors, ECOG 0-1, and a planned comprehensive molecular tumor analysis.

Probably not a fit

Patients with hematologic cancers or those unable to consent may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study uses local AI models to analyze comprehensive molecular tumor profiles and generate potential treatment options. The AI-generated options are then compared to actual personalized therapy recommendations to see if they are non-inferior. Eligible participants are adults with advanced solid tumors, good performance status (ECOG 0-1), and a planned comprehensive molecular analysis. The study is led by Charité – Universitätsmedizin Berlin with no listed collaborators and takes place at Charité in Berlin.

Why it matters

Potential benefit: If successful, AI-generated recommendations could support physicians by offering consistent, data-driven treatment options alongside standard care.

How similar studies have gone: Similar approaches using AI to assist oncology decision-making have shown promise, though this specific non-interventional comparison is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* advanced solid tumor
* \>=18years
* ECOG 0-1
* comprehensive molecular tumor analysis planned

Exclusion Criteria:

* lack of capacity to consent
* hematological neoplasm

Where it's running

  • Charité - Universitätsmedizin Berlin
    Berlin, Germany
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.