How three toric intraocular lenses rotate after cataract surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective comparative cohort study enrolling adults having phacoemulsification with implantation of one of three commercially available toric intraocular lenses (TECNIS Toric II ZCU, AcrySof IQ Toric, AT TORBI 709M). Postoperative lens rotation is measured by registering retroillumination photographs to an end-of-surgery baseline using iris and scleral landmarks. Patients are followed on postoperative day 1, day 3, week 1, week 2, month 1, and month 3 to define the time course of rotational changes. Associations between rotational outcomes and ocular biometric parameters are analyzed using linear mixed-effects models to inform individualized lens selection and perioperative management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 years or older with age-related cataract scheduled for phacoemulsification cataract surgery.
* Presence of regular corneal astigmatism requiring toric intraocular lens implantation.
* Eligible for implantation of one of the three study toric intraocular lenses based on preoperative evaluation.
* Ability to understand the study procedures and provide written informed consent.

Exclusion Criteria:

* History of prior ocular surgery in the study eye.
* History of ocular trauma in the study eye.
* Irregular corneal astigmatism or corneal pathology affecting reliable biometric measurement.
* Intraoperative complications, including anterior capsular tear or posterior capsular rupture.
* Inadequate pupillary dilation during surgery or postoperative examinations.
* Evidence of zonular weakness, zonular dialysis, or lens subluxation.
* Active ocular infection or inflammation.
* Any other ocular or systemic condition judged by the investigator to potentially affect intraocular lens stability or study outcomes.

Where it's running

• Eye and ENT hospital of Fudan University
  Shanghai, Shanghai Municipality, China Recruiting

Study contacts

• Principal investigator: Jin Yang — Fudan University
• Study coordinator: Xuanqiao Lin
• Email: 1532483480@qq.com
• Phone: +8615088920668

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Rotational Stability of the Acunex Vario Toric

  This study tests whether the Acunex Vario toric extended-depth-of-focus intraocular lens stays stable in rotation and effectively reduces astigmatism for people undergoing cataract surgery.

  Recruiting Vienna Institute for Research in Ocular Surgery · Vienna · NCT07925840

• Anterior segment anatomy assessment with swept-source OCT in eye surgery patients

  This study tests whether swept-source OCT can detail front-eye anatomy in patients undergoing anterior segment eye surgery.

  Recruiting Nanfang Hospital, Southern Medical University · Guangzhou, Guangdong · NCT07903454

• MiLOOP-assisted cataract surgery for dense cataracts

  In people with dense cataracts, this study tests whether using the miLOOP device during cataract surgery can protect corneal cells and reduce ultrasound energy, compared with standard surgery.

  Recruiting Universiti Kebangsaan Malaysia Medical Centre · Cheras, Kuala Lumpur · NCT07898007

• Visual adaptation and quality of life after different IOL implantation options

  This study follows adults who have cataracts and receive bilateral multifocal or mixed IOLs to see how their vision and daily life improve over 6 months.

  Recruiting Sichuan Academy of Medical Sciences · Chengdu · NCT07740590

• Corneal Biomechanics and Surgical Astigmatism after Cataract Surgery in Pseudoexfoliation

  This study tests how the cornea's biomechanical properties before cataract surgery relate to the amount of blinking surgically induced astigmatism, comparing people with pseudoexfoliation to those without.

  Recruiting Eye Clinic Medic Zuljan Jukic · Split, Splitsko-dalmatinska County · NCT07722247

• Neuroplastic pain education and guided breathing during awake cataract surgery

  This trial tests whether the STEIN Protocol, a non-drug approach with pain education, guided imagery, and paced breathing, helps adults having cataract surgery require less pain medicine and feel less anxious.

  Recruiting University of California, Los Angeles · Los Angeles, California · NCT07715591

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.