How surgical approach affects posture-breathing coordination after lobectomy
Impact of Surgical Approach on Adaptation of Posture-respiratory Coupling
This study will see if minimally invasive lobectomy (robotic or video-assisted) versus traditional thoracotomy changes how posture and breathing coordinate in people having surgery for resectable non-small cell lung cancer.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Assistance Publique - Hôpitaux de Paris Academic / other |
| Locations | 1 site (Paris) |
| Trial ID | NCT06276530 on ClinicalTrials.gov |
What this trial studies
This single-center interventional study enrolls patients with resectable non-small cell lung cancer scheduled for lobectomy and compares conventional posterolateral thoracotomy with minimally invasive approaches (VATS/RATS). Investigators will perform EOS musculoskeletal imaging, optoelectronic movement capture, and stabilometric force-platform measurements before and after surgery to quantify posture, alignment, balance, and breathing-related movements. The protocol aims to link objective postural and respiratory adaptations to differences in postoperative pain, complications, and quality of life seen with minimally invasive techniques. By identifying physiopathologic mechanisms, the work seeks to explain why VATS/RATS often lead to faster recovery than open thoracotomy.
Who should consider this trial
Good fit: Adults with resectable non-small cell lung carcinoma admitted for lobectomy who will undergo either conventional posterolateral thoracotomy or minimally invasive (robotic or video-assisted) lobectomy are ideal candidates.
Not a fit: Patients requiring extended lung resections, those with unresectable disease, or people unable to attend the in-person imaging and motion testing are unlikely to benefit from or be eligible for this protocol.
Why it matters
Potential benefit: If successful, the findings could help guide surgical choice and rehabilitation to reduce postoperative pain and speed recovery of breathing and posture after lobectomy, improving patients' quality of life.
How similar studies have performed: Prior studies have shown minimally invasive lobectomy reduces postoperative pain and complications compared with thoracotomy, but applying detailed posture-respiratory coupling measurements to explain that benefit is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients admitted for major lung resection * Surgical approach by conventional postern-lateral thoracotomy * Surgical approach by minimally invasive RATS Exclusion Criteria: \- Extended lung resection
Where this trial is running
Paris
- Department of Thoracic and Vascular Surgery Tenon University Hospital — Paris, France (Recruiting)
Study contacts
- Principal investigator: Harry ETIENNE, M.D., PhD — Assistance Publique - Hôpitaux de Paris
- Study coordinator: Harry ETIENNE, M.D., PhD Degree
- Email: harry.etienne@aphp.fr
- Phone: 06.67.96.82.89
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.