Clinical trial Recruiting at 1 site Observational Ages 18 and up Men only

How retroperitoneal lymph node dissection affects urination and sexual function

Official title: Voiding, Erectile and Ejaculatory Function After Retroperitoneal Lymph Node Dissection for Testicular Cancer

Run by Jagiellonian University · NCT06954233 · Data updated 2026-11-12

This project will see if retroperitoneal lymph node dissection (RPLND) for testicular cancer changes urination, ejaculation, erections, and quality of life in adult men.

Quick facts

Study typeObservational
Ages18 Years and up
SexMen only
Enrollment20 (estimated)
SponsorJagiellonian University
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Krakow, Malopolska)
StatusRecruiting
StartedMay 14, 2025
Main results expectedDecember 2027
Study endsDecember 2027
Registry record updatedJuly 16, 2025
Trial IDNCT06954233 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adult men with testicular cancer who are scheduled to undergo RPLND and can provide informed consent are ideal candidates for this study.

Probably not a fit

Men with a prior RPLND or those with irreversible preexisting urinary or sexual dysfunction unrelated to their current treatment are unlikely to benefit from this study's findings.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective observational study that follows adult men undergoing RPLND for testicular cancer with measurements taken before surgery and at scheduled visits up to six months after the operation. Participants complete validated patient-reported outcome measures for urinary symptoms, ejaculatory and erectile function, and quality of life, and undergo non-invasive tests including uroflowmetry and post-void residual ultrasound. The design pairs subjective questionnaires with objective flow and volume measurements to characterize the timing and magnitude of functional changes after RPLND. Data will be used to describe typical recovery patterns and identify factors associated with worse urinary or sexual outcomes.

Why it matters

Potential benefit: If successful, the results could help clinicians predict, counsel about, and manage urinary and sexual side effects after RPLND, improving postoperative care and rehabilitation.

How similar studies have gone: Previous research has established that RPLND commonly affects ejaculation, but prospective, systematic data on effects on urine flow and erectile function are limited, making this partly novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult male with testicular cancer undergoing retroperitoneal lymph node dissection (RPLND)

Exclusion Criteria:

* History of RPLND
* Lack of consent

Where it's running

  • Jagiellonian University Medical College
    Krakow, Malopolska, Poland
    Recruiting

Study contacts

  • Principal investigator: Anna K. Czech, M.D. — Jagiellonian University
  • Study coordinator: Anna K. Czech, M.D., Ph.D.
  • Email: aka.czech@uj.edu.pl
  • Phone: +48124002500

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.