How new metabolites affect valvular heart disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational, long-term follow-up study of adults with clinically diagnosed valvular heart disease conducted at the First Affiliated Hospital of Sun Yat-sen University. Investigators will collect clinical data and biological specimens, then perform metabolite testing on tissue samples to identify novel metabolic markers. The study aims to link metabolic signatures to risk factors, mechanisms of valve damage, and patient prognosis. Results will be used to generate hypotheses for future diagnostic biomarkers or targeted interventions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age ≥18 years, gender is not limited.
2. Clinical diagnosis of heart valve disease (including aortic stenosis, aortic valve closure insufficiency due to different etiologies, mitral stenosis, mitral valve closure insufficiency, pulmonic stenosis, pulmonic valve closure insufficiency, tricuspid stenosis and tricuspid closure insufficiency due to different etiologies )

Exclusion Criteria:

Patients unable to provide informed consent

Where it's running

• The First Affiliated Hospital of Sun Yat-sen Univerity
  Guangzhou, Guangdong, China Recruiting

Study contacts

• Study coordinator: Xiaodong Zhuang
• Email: zhuangxd3@mail.sysu.edu.cn
• Phone: +8613760755035

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.