How gallbladder is taken out during laparoscopy: subxiphoid vs infraumbilical port
Official title: Comparison of Gallbladder Extraction Via the Subxiphoid Port and the Infraumbilical Port During Laparoscopic Cholecystectomy: A Prospective Randomized Clinical Trial
Run by King Edward Medical University · NCT07672145 · Data updated 2026-11-12
This trial tests whether removing the gallbladder through the subxiphoid port is as safe and comfortable as the usual infraumbilical port in people with gallstone disease needing laparoscopic gallbladder removal.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 60 Years |
| Sex | All |
| Enrollment | 66 (estimated) |
| Sponsor | King Edward Medical University Academic / other |
| Locations | 1 site (Lahore, Punjab Province) |
| Status | Recruiting |
| Started | May 20, 2026 |
| Main results expected | July 15, 2026 |
| Study ends | August 15, 2026 |
| Registry record updated | June 26, 2026 |
| Trial ID | NCT07672145 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18-60 with symptomatic gallstones scheduled for elective laparoscopic cholecystectomy and without diabetes, ASA I-II, including those with acute or empyematous cholecystitis.
✕Probably not a fit
Patients who require conversion to open surgery or have conditions excluding benefit, such as diabetes mellitus type 2, may not benefit from this approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized controlled trial compares two extraction routes for the gallbladder during elective laparoscopic cholecystectomy: subxiphoid port versus infraumbilical port. Participants are adults 18-60 with symptomatic gallstones, ASA I-II, undergoing surgery at Mayo Hospital in Lahore. After standard four-port laparoscopic surgery and endo-bag containment, the gallbladder is retrieved through either the subxiphoid or infraumbilical port under direct vision, with postoperative pain and recovery monitored for the first 24 hours and additional assessments through the first week. Primary and secondary outcomes include postoperative pain scores and wound-related complications, aiming to identify if the subxiphoid route offers advantages or similar safety to the conventional route.
Why it matters
Potential benefit: If successful, the subxiphoid retrieval could reduce postoperative pain and wound complications for gallbladder removal.
How similar studies have gone: Previous surgical approaches exploring port choices have shown variable results; this study investigates a specific retrieval site with direct comparison.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged between 18 to 60 years. * Diagnosed with symptomatic gallstones on ultrasonography. * American Society of Anesthesiologists (ASA) physical status I-II. * Scheduled for elective laparoscopic cholecystectomy. * Presence of acute or empyematous cholecystitis Exclusion Criteria: * Intraoperative conversion to open cholecystectomy. * Diagnosed with Diabetes mellitus type 2.
Where it's running
-
Department of Surgery ,Mayo Hospital
Lahore, Punjab Province, Pakistan Recruiting
Study contacts
- Principal investigator: Dr Muhammad Zeeshan Sarwar, MBBS,FCPS — King Edward Medical University
- Study coordinator: Dr Abdur Rehman, MBBS
- Email: oabdurrehmanazad@gmail.com
- Phone: +92 331 4344721
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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This randomized trial tests two less-invasive gallbladder drainage methods to see which works better for people with acute gallbladder infection who aren’t candidates for surgery.
-
Cholecystitis: EUS-guided Gallbladder Drainage vs Cyst removal by LCC in older adults
In people aged 75 and up with acute cholecystitis, this study tests whether an endoscopic drainage procedure (EUS-GBD) works as well as the standard gallbladder removal surgery (LCC).
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Deep learning rapid MRI for preoperative evaluation of acute cholecystitis.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.