Timing for Gallbladder Surgery After Drainage in Acute Cholecystitis
Official title: Optimal Timing for Laparoscopic Cholecystectomy After Percutaneous Cholecystostomy in Acute Cholecystitis Tokyo II/III Setting: A Randomized Clinical Trial
Run by Hospital Arnau de Vilanova · NCT06476054 · Data updated 2026-11-12
This study is testing whether having gallbladder surgery sooner or later after drainage helps people with acute cholecystitis recover better and have fewer complications.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 146 (estimated) |
| Sponsor | Hospital Arnau de Vilanova Academic / other |
| Locations | 1 site (Lleida) |
| Status | Recruiting |
| Started | February 1, 2024 |
| Main results expected | August 1, 2026 |
| Study ends | August 1, 2027 |
| Registry record updated | June 28, 2024 |
| Trial ID | NCT06476054 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 years old who are scheduled for cholecystectomy following percutaneous drainage.
✕Probably not a fit
Patients with significant comorbidities that prevent proper follow-up or those who cannot undergo the procedure will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to determine the optimal timing for laparoscopic cholecystectomy in patients who have undergone percutaneous cholecystostomy for acute cholecystitis. It will compare outcomes between early and late surgery to assess recurrence rates and associated morbidity and mortality. The study will involve multiple centers and will collect extensive pre-operative and post-operative data to ensure a comprehensive analysis. The recruitment period for participants is set for 18 months.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and reduced recurrence rates for patients with acute cholecystitis.
How similar studies have gone: While there is limited high-quality evidence on this specific timing issue, similar studies have explored surgical timing in other contexts, indicating potential for impactful findings.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients over 18 years of age * patients candidates for cholecystectomy, in scheduled surgery * patients who accept participation and sign informed consent form Exclusion Criteria: * According to the principal investigator criteria, for reasons that make it impossible to correctly follow the treatment. * Presence of morbidity associated with the procedure that delays or makes treatment impossible.
Where it's running
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Hospital Universitari Arnau de Vilanova
Lleida, Spain Recruiting
Study contacts
- Principal investigator: 605387406 Vela Polanco, Dr — Hospital Arnau de Vilanova
- Study coordinator: Fulthon Frank Vela Polanco, Dr
- Email: ffvela.lleida.ics@gencat.cat
- Phone: 0034605387406
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Repeat gallbladder ultrasound in the ED to detect early acute cholecystitis
In adults with abdominal pain and an initially non-diagnostic gallbladder ultrasound in the emergency department, this study tests whether a second ultrasound can help confirm acute cholecystitis sooner.
-
How gallbladder is taken out during laparoscopy: subxiphoid vs infraumbilical port
This trial tests whether removing the gallbladder through the subxiphoid port is as safe and comfortable as the usual infraumbilical port in people with gallstone disease needing laparoscopic gallbladder removal.
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Preventing hernias after emergency surgery
See how often adults who have emergency abdominal surgery develop postoperative hernias and which risk factors they have.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.