How Fitness and Body Fat Affect Blood Sugar and Blood Vessel Health After Short-Term Inactivity
Official title: Interactive Roles of Cardiorespiratory Fitness and Adiposity on Recovery of Impaired Glucose and Vascular Control After Physical Inactivity
Run by Miami University · NCT06842225 · Data updated 2026-11-12
This study tests how existing fitness and body fat influence recovery of glucose control and vascular function after a period of reduced activity.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 40 Years |
| Sex | All |
| Enrollment | 48 (estimated) |
| Sponsor | Miami University Academic / other |
| Locations | 1 site (Oxford, Ohio) |
| Status | Recruiting |
| Started | October 8, 2025 |
| Main results expected | May 15, 2028 |
| Study ends | June 30, 2029 |
| Registry record updated | October 9, 2026 |
| Trial ID | NCT06842225 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18–40 with varying fitness and visceral fat levels who can safely participate in short-term activity changes.
✕Probably not a fit
Individuals with certain cardiovascular, metabolic, or pulmonary conditions or who cannot safely complete the activities may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Healthy adults aged 18–40 will undergo a period of reduced physical activity to see how their current fitness level and visceral fat affect recovery of glucose control and vascular function. Researchers will measure glucose responses, vascular function, and possibly how varying fat levels impact recovery. The study also aims to provide undergraduate students with hands-on experience in clinical research methods. Details about specific procedures and analyses have been piloted in prior work. This description reflects the planned approach and scope of the trial at a high level.
Why it matters
Potential benefit: If successful, findings could help tailor activity guidelines to individual fitness and body fat profiles to improve glucose control and vascular health after inactivity.
How similar studies have gone: Previous research in related areas indicates that fitness and adiposity can influence cardiometabolic responses, supporting the relevance of this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Males and females 18 to 40 years of age. * Ability to safely ride an electric scooter (e-scooter) for at least 10 minutes. * Active (\>7000 steps per day, walking \> 1 mile a day outside) * Stable body weight for at least 1 year * aerobic fitness level, CRF is \< 9 and \>14 METS * Visceral adipose tissue \<130 cm2 or ≥130 cm2 for men and \<100 cm2 or ≥100 cm for women Exclusion Criteria: * Any injury preventing them from exercising regularly at the time of the screening. * Implantable defibrillator or pacemaker * Active cancer * Alcohol or drug abuse * Use of an assistive walking device * Presence of significant signs/symptoms of cardiovascular, metabolic, or pulmonary disease (determined from the American College of Sports Medicine (ACSM) Health History Questionnaire) * Daily vitamin consumption of \> 500mg per day during the study * Acetaminophen or aspirin use during the study
Where it's running
-
Phillips Hall
Oxford, Ohio, United States Recruiting
Study contacts
- Study coordinator: Kevin Ballard, PhD
- Email: ballarkd@miamioh.edu
- Phone: 513-529-9247
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.