Home-use dual-light antibacterial therapy for peri-implant mucositis around full-arch implants

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot randomized, two-arm, parallel-group trial evaluates the clinical and microbiological effects of adjunctive home-use dual-light antibacterial photodynamic therapy in adults with peri-implant mucositis who have screw-retained full-arch implant-supported prostheses. Participants receive usual professional cleaning and personalized oral hygiene instructions, with or without the at-home light device, over a short-term follow-up. The study aims to see if the device reduces gum bleeding, lowers probing depths, and decreases pathogenic bacteria compared with usual care alone. It is conducted at Odonto-Maxillo-Facial Hospital in Ho Chi Minh City under a single-blind design. The intervention combines antimicrobial photodynamic therapy with antibacterial blue light as a non-antibiotic adjunct to supportive peri-implant care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 years or older who agree to participate and provide written informed consent.
* Rehabilitated with a screw-retained full-arch implant-supported fixed prosthesis (All-on-4, All-on-6 or All-on-X) delivered at least 3 months before enrolment.
* Diagnosed with peri-implant mucositis according to the 2017 World Workshop case definitions.
* HbA1c below 7.0% and stable systemic health.
* Non-smoker for at least the preceding 6 months.
* Willing to attend all scheduled follow-up visits at 2 and 4 weeks and to comply with the home-use protocol.

Exclusion Criteria:

* Disability or severe motor impairment limiting the ability to perform the oral hygiene procedures required by the study.
* Long-term antibiotic therapy.
* Immunodeficiency.
* Long-term corticosteroid therapy.
* History of organ transplantation.
* Refusal to participate.

Where it's running

• Odonto-Maxillo-Facial Hospital in Ho Chi Minh City
  Ho Chi Minh City, Cau Ong Lanh Ward, Vietnam Recruiting

Study contacts

• Study coordinator: Huy Cong Ho, Doctor of Dental Surgery (DDS)
• Email: conghuy.ho.9@gmail.com
• Phone: 84 + 827555408

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.