Home-based exercise program for Veterans recovering from COVID-19
Official title: Home-Based Exercise Tele-Rehabilitation in High-Risk Veterans: Impact of COVID-19 Exposure and Socioeconomic Factors
Run by VA Office of Research and Development · NCT05425264 · Data updated 2026-11-12
This study tests whether a home-based exercise program can help Veterans who have recovered from COVID-19 improve their heart and lung health and physical abilities.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 50 Years to 85 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | VA Office of Research and Development Federal |
| Locations | 1 site (Baltimore, Maryland) |
| Status | Recruiting |
| Started | June 29, 2023 |
| Main results expected | September 30, 2027 |
| Study ends | June 30, 2028 |
| Registry record updated | November 6, 2026 |
| Trial ID | NCT05425264 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are Veterans who have documented COVID-19 infection more than 90 days ago and have specific comorbid conditions.
✕Probably not a fit
Patients with recent myocardial infarction, severe heart failure, or other serious health conditions may not benefit from this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This program investigates the effects of a home-based, supervised group exercise tele-rehabilitation on Veterans who have recovered from COVID-19. It aims to address the lasting impacts of the virus on cardiopulmonary health and physical function, particularly in older Veterans with comorbidities. Utilizing VA Video Connect, the study will deliver exercise sessions remotely, allowing participants to engage in rehabilitation safely from their homes. The research will also explore healthcare disparities related to COVID-19 and their effects on functional decline.
Why it matters
Potential benefit: If successful, this program could significantly improve the physical function and quality of life for Veterans recovering from COVID-19.
How similar studies have gone: Other studies have shown promise in tele-rehabilitation approaches for improving health outcomes, making this a potentially effective intervention.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Veteran * documented COVID-19 \> 90 days ago * diagnosis of 2 of following conditions: hypertension, diabetes, cardiovascular disease, chronic kidney disease, chronic obstructive pulmonary disease OR 1 condition and BMI \> 30 kilograms per square meter (kg/m2) Exclusion Criteria: * myocardial infarction (within 3 months) * exertional or unstable angina (chest pain that limits activity) * severe congestive heart failure (EF \< 20% in last year or NYHA Classification III or IV) * uncontrolled hypertension (systolic blood pressure\>180 \&/or diastolic blood pressure\> 110 millimeters of mercury at screening) * screening electrocardiogram (EKG) with ischemia, complex arrhythmia, or high-grade block (per Minnesota Code) * poorly controlled diabetes mellitus (fasting blood sugar\>200 milligrams per deciliter, random blood sugar \> 299 milligrams per deciliter, or HbA1C \> 10) * treatment for cancer except skin cancer (within 3 months) * peripheral vascular disease with claudication * severe arthritis limiting ambulation * neurologic disease limiting ambulation (weakness requiring assist device; severe neuropathy) * end stage liver disease (decompensated liver disease) * End stage renal failure (dialysis) * severe pulmonary disease (home oxygen, admission for dyspnea or pneumonia within 1 month) * high fall risk (history of falls, bone fracture) * dementia (based on Evaluation to Consent) * signs or symptoms of any medical comorbidity that would preclude exercise testing or training * exercises on routine basis (structured aerobic exercise \> 3 times per week)
Where it's running
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Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD
Baltimore, Maryland, United States Recruiting
Study contacts
- Principal investigator: Alice S. Ryan, PhD — Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD
- Study coordinator: Alice S Ryan, PhD
- Email: Alice.Ryan@va.gov
- Phone: (410) 605-7851
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Natural history of COVID-19 in hospitalized adults
This project will follow adults hospitalized with COVID-19 to see how the illness and treatments change over time.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.